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Erectile Dysfunction and Cardiovascular Events in Diabetic Men: A Meta-analysis of Observational Studies

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  • Tomohide Yamada
  • Kazuo Hara
  • Hitomi Umematsu
  • Ryo Suzuki
  • Takashi Kadowaki

Abstract

Background: Several studies have shown that erectile dysfunction (ED) influences the risk of cardiovascular events (CV events). However, a meta-analysis of the overall risk of CV events associated with ED in patients with diabetes has not been performed. Methodology/Principal Findings: We searched MEDLINE and the Cochrane Library for pertinent articles (including references) published between 1951 and April 22, 2012. English language reports of original observational cohort studies and cross-sectional studies were included. Pooled effect estimates were obtained by random effects meta-analysis. Conclusion/Significance: ED was associated with an increased risk of CV events in diabetic patients. Prevention and early detection of cardiovascular disease are important in the management of diabetes, especially in view of the rapid increase in its prevalence.

Suggested Citation

  • Tomohide Yamada & Kazuo Hara & Hitomi Umematsu & Ryo Suzuki & Takashi Kadowaki, 2012. "Erectile Dysfunction and Cardiovascular Events in Diabetic Men: A Meta-analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 7(9), pages 1-7, September.
  • Handle: RePEc:plo:pone00:0043673
    DOI: 10.1371/journal.pone.0043673
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    References listed on IDEAS

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