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Fabricating supramolecular pre-emergence herbicide CPAM-BPyHs for farming herbicide-resistant rice

Author

Listed:
  • Ronghua Chen

    (South China Agricultural University
    Guangdong Academy of Sciences)

  • Chaozheng Li

    (South China Agricultural University)

  • Di Zhao

    (South China Agricultural University)

  • Guili Yang

    (South China Agricultural University)

  • Lingda Zeng

    (South China Agricultural University)

  • Fei Lin

    (South China Agricultural University)

  • Hanhong Xu

    (South China Agricultural University)

Abstract

Controlling weeds before their emergence is crucial for minimizing their impacts on crop yield and quality. Bipyridyl herbicides (BPyHs), a class of highly effective and broad-spectrum herbicides, cannot be used as pre-emergence herbicides because they can be absorbed and inactivated by negatively charged soil after application. Here, we design and fabricate an adsorbed-but-active supramolecular pre-emergence herbicide consisting of cationic polyacrylamide and bipyridyl herbicides (CPAM-BPyHs). CPAM is a positively charged polymer. It can preferentially bind to soil particles and shift their electric potential to a more positive value. Thus, it prevents not only runoff but also inactivation of BPyHs. We also develop a BPyHs-resistant rice line by mutation of the gene encoding L-type amino acid transporter 5 (OsLAT5). Field trial results show that the weed control efficiency of CPAM-diquat for direct-seeded herbicide-resistant rice line exceeds 90%. The herbicidal activity can maintain up to one month with only one application. This work offers a method for rice weed control and provides insights into the design of pesticides to prevent soil inactivation and runoff.

Suggested Citation

  • Ronghua Chen & Chaozheng Li & Di Zhao & Guili Yang & Lingda Zeng & Fei Lin & Hanhong Xu, 2025. "Fabricating supramolecular pre-emergence herbicide CPAM-BPyHs for farming herbicide-resistant rice," Nature Communications, Nature, vol. 16(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-59582-9
    DOI: 10.1038/s41467-025-59582-9
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    References listed on IDEAS

    as
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