Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease
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DOI: 10.1038/s41467-022-30875-7
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- Kevin Huynh & Wei Ling Florence Lim & Corey Giles & Kaushala S. Jayawardana & Agus Salim & Natalie A. Mellett & Adam Alexander T. Smith & Gavriel Olshansky & Brian G. Drew & Pratishtha Chatterjee & Ia, 2020. "Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease," Nature Communications, Nature, vol. 11(1), pages 1-11, December.
- Karoline Kuchenbaecker & Nikita Telkar & Theresa Reiker & Robin G. Walters & Kuang Lin & Anders Eriksson & Deepti Gurdasani & Arthur Gilly & Lorraine Southam & Emmanouil Tsafantakis & Maria Karalefthe, 2019. "The transferability of lipid loci across African, Asian and European cohorts," Nature Communications, Nature, vol. 10(1), pages 1-10, December.
- Zhihong Zhu & Zhili Zheng & Futao Zhang & Yang Wu & Maciej Trzaskowski & Robert Maier & Matthew R. Robinson & John J. McGrath & Peter M. Visscher & Naomi R. Wray & Jian Yang, 2018. "Causal associations between risk factors and common diseases inferred from GWAS summary data," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Karsten Suhre & So-Youn Shin & Ann-Kristin Petersen & Robert P. Mohney & David Meredith & Brigitte Wägele & Elisabeth Altmaier & Panos Deloukas & Jeanette Erdmann & Elin Grundberg & Christopher J. Ham, 2011. "Human metabolic individuality in biomedical and pharmaceutical research," Nature, Nature, vol. 477(7362), pages 54-60, September.
- Rubina Tabassum & Joel T. Rämö & Pietari Ripatti & Jukka T. Koskela & Mitja Kurki & Juha Karjalainen & Priit Palta & Shabbeer Hassan & Javier Nunez-Fontarnau & Tuomo T. J. Kiiskinen & Sanni Söderlund , 2019. "Genetic architecture of human plasma lipidome and its link to cardiovascular disease," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Tianxiao Huan & Roby Joehanes & Ci Song & Fen Peng & Yichen Guo & Michael Mendelson & Chen Yao & Chunyu Liu & Jiantao Ma & Melissa Richard & Golareh Agha & Weihua Guan & Lynn M. Almli & Karen N. Conne, 2019. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Bryan N Howie & Peter Donnelly & Jonathan Marchini, 2009. "A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies," PLOS Genetics, Public Library of Science, vol. 5(6), pages 1-15, June.
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- Kenneth A. Wilson & Sudipta Bar & Eric B. Dammer & Enrique M. Carrera & Brian A. Hodge & Tyler A. U. Hilsabeck & Joanna Bons & George W. Brownridge & Jennifer N. Beck & Jacob Rose & Melia Granath-Pane, 2024. "OXR1 maintains the retromer to delay brain aging under dietary restriction," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Aleksandar Dakic & Jingqin Wu & Tingting Wang & Kevin Huynh & Natalie Mellett & Thy Duong & Habtamu B. Beyene & Dianna J. Magliano & Jonathan E. Shaw & Melinda J. Carrington & Michael Inouye & Jean Y., 2024. "Imputation of plasma lipid species to facilitate integration of lipidomic datasets," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
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