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Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom

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Listed:
  • Long H. Nguyen

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School
    Harvard T.H. Chan School of Public Health)

  • Amit D. Joshi

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School)

  • David A. Drew

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School)

  • Jordi Merino

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School
    Broad Institute of MIT and Harvard)

  • Wenjie Ma

    (Massachusetts General Hospital and Harvard Medical School)

  • Chun-Han Lo

    (Massachusetts General Hospital and Harvard Medical School)

  • Sohee Kwon

    (Massachusetts General Hospital and Harvard Medical School)

  • Kai Wang

    (Massachusetts General Hospital and Harvard Medical School
    Harvard T.H. Chan School of Public Health)

  • Mark S. Graham

    (King’s College London)

  • Lorenzo Polidori

    (Zoe Ltd)

  • Cristina Menni

    (King’s College London)

  • Carole H. Sudre

    (King’s College London)

  • Adjoa Anyane-Yeboa

    (Massachusetts General Hospital and Harvard Medical School)

  • Christina M. Astley

    (Broad Institute of MIT and Harvard
    Boston Children’s Hospital and Harvard Medical School)

  • Erica T. Warner

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School)

  • Christina Y. Hu

    (Zoe Ltd)

  • Somesh Selvachandran

    (Zoe Ltd)

  • Richard Davies

    (Zoe Ltd)

  • Denis Nash

    (City University of New York (CUNY)
    City University of New York (CUNY))

  • Paul W. Franks

    (Lund University)

  • Jonathan Wolf

    (Zoe Ltd)

  • Sebastien Ourselin

    (King’s College London)

  • Claire J. Steves

    (King’s College London)

  • Tim D. Spector

    (King’s College London)

  • Andrew T. Chan

    (Massachusetts General Hospital and Harvard Medical School
    Massachusetts General Hospital and Harvard Medical School
    Harvard T.H. Chan School of Public Health
    Massachusetts Consortium on Pathogen Readiness)

Abstract

Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteered to take part in the smartphone-based COVID Symptom Study (March 2020-February 2021) and used logistic regression to estimate odds ratios of vaccine hesitancy and uptake. In the U.S. (n = 87,388), compared to white participants, vaccine hesitancy was greater for Black and Hispanic participants and those reporting more than one or other race. In the U.K. (n = 1,254,294), racial and ethnic minority participants showed similar levels of vaccine hesitancy to the U.S. However, associations between participant race and ethnicity and levels of vaccine uptake were observed to be different in the U.S. and the U.K. studies. Among U.S. participants, vaccine uptake was significantly lower among Black participants, which persisted among participants that self-reported being vaccine-willing. In contrast, statistically significant racial and ethnic disparities in vaccine uptake were not observed in the U.K sample. In this study of self-reported vaccine hesitancy and uptake, lower levels of vaccine uptake in Black participants in the U.S. during the initial vaccine rollout may be attributable to both hesitancy and disparities in access.

Suggested Citation

  • Long H. Nguyen & Amit D. Joshi & David A. Drew & Jordi Merino & Wenjie Ma & Chun-Han Lo & Sohee Kwon & Kai Wang & Mark S. Graham & Lorenzo Polidori & Cristina Menni & Carole H. Sudre & Adjoa Anyane-Ye, 2022. "Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-28200-3
    DOI: 10.1038/s41467-022-28200-3
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    Cited by:

    1. Yoshiki B. Kurata & Ardvin Kester S. Ong & Ranice Ysabelle B. Ang & John Karol F. Angeles & Bianca Danielle C. Bornilla & Justine Lian P. Fabia, 2023. "Factors Affecting Flood Disaster Preparedness and Mitigation in Flood-Prone Areas in the Philippines: An Integration of Protection Motivation Theory and Theory of Planned Behavior," Sustainability, MDPI, vol. 15(8), pages 1-24, April.
    2. John Iceland & Eric Silver & Kerby Goff, 2023. "Moral intuitions and vaccine hesitancy during the COVID‐19 pandemic," Social Science Quarterly, Southwestern Social Science Association, vol. 104(3), pages 230-247, May.
    3. Sahabi Kabir Sulaiman & Muhammad Sale Musa & Fatimah Isma’il Tsiga-Ahmed & Abdulwahab Kabir Sulaiman & Abdulaziz Tijjani Bako, 2024. "A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV," Nature Human Behaviour, Nature, vol. 8(1), pages 100-114, January.
    4. Emmanuel Ogiemwonyi Arakpogun & Padmali Rodrigo & Femi Olan, 2022. "“You Shall Not Pass” without a Jab: An Institutional Theory Perspective to COVID-19 Vaccine Passport Policies," IJERPH, MDPI, vol. 19(21), pages 1-18, October.

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