IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v22y2025i5p672-d1641918.html
   My bibliography  Save this article

Impact of Praziquantel Mass Drug Administration on Schistosomiasis: A Comparison of Prevalence and Risk Factors Between Treated School Aged Children and Untreated Adults in Abuja, Nigeria

Author

Listed:
  • Solomon M. Jacob

    (Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria
    Department of Public Health, Federal Ministry of Health, P.M.B. 083, Garki, Abuja 900108, Nigeria)

  • Sophie Y. Akinbo

    (Department of Molecular Biology Diagnosis, Northwestern Memorial Hospital, Chicago, IL 60611, USA)

  • Akinola S. Oluwole

    (Sightsavers Country Office, Abuja 900271, Nigeria)

  • Temitope Agbana

    (AiDx Medical Bv, 2641 KM Pijnacker, The Netherlands
    Sustainable Design Engineering, Delft University of Technology, 2628 CE Delft, The Netherlands)

  • Zainab Omoruyi

    (Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria)

  • Michael A. Okungbowa

    (Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria)

  • Jan-Carel Diehl

    (Sustainable Design Engineering, Delft University of Technology, 2628 CE Delft, The Netherlands)

  • Fredrick O. Akinbo

    (Department of Medical Laboratory Science, University of Benin, P.M.B. 1154, Benin City 300283, Nigeria)

Abstract

Introduction: One of the global strategies for the elimination of schistosomiasis is by Mass Drug Administration (MDA) of a single oral dose of praziquantel (40 mg/kg) without a prior individual diagnosis, with a target of >75% treatment coverage among school-aged children. This study was conducted to determine the endemicity of schistosomiasis among school-aged children and adults in Abuja, Nigeria. Methods: A total of 1370 participants were recruited, which consisted of 667 (48.67%) males and 703 (51.31%) females. Urine and stool specimens were collected from each participant and analyzed using standard procedures. Results: The overall prevalence of schistosomiasis was 27.5% in this study with Abuja Municipal having the highest prevalence of 49%, while the least (6.1%) was reported in Bwari LAC. The prevalence of schistosomiasis significantly differs ( p < 0.05) between the area councils. The location of communities significantly affected the prevalence of schistosomiasis in Abaji, AMAC, and Gwagwalada LACs ( p < 0.005). The Schistosoma recovered in this study were S. haematobium and S. mansoni . The prevalence of schistosomiasis increased from the baseline of 21.1% to 49% in Gwagwalada LAC. Gender significantly affected the prevalence of schistosomiasis as more males were infected (33.1%) than their female counterparts (22.2%) ( p < 0.05). The prevalence of schistosomiasis was 31% and 23.9% among SAC and adults, respectively. The participants’ activities in the river significantly affected the prevalence of schistosomiasis in this study ( p < 0.05). Conclusions: The clamour for urgent government and non-government intervention through alternate sources of water like boreholes or pipe-borne water, as well as implementing a behavioural change campaign across the communities to prevent the recurrence, are advocated.

Suggested Citation

  • Solomon M. Jacob & Sophie Y. Akinbo & Akinola S. Oluwole & Temitope Agbana & Zainab Omoruyi & Michael A. Okungbowa & Jan-Carel Diehl & Fredrick O. Akinbo, 2025. "Impact of Praziquantel Mass Drug Administration on Schistosomiasis: A Comparison of Prevalence and Risk Factors Between Treated School Aged Children and Untreated Adults in Abuja, Nigeria," IJERPH, MDPI, vol. 22(5), pages 1-18, April.
  • Handle: RePEc:gam:jijerp:v:22:y:2025:i:5:p:672-:d:1641918
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/22/5/672/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/22/5/672/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:22:y:2025:i:5:p:672-:d:1641918. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.