IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i2p1125-d1029074.html
   My bibliography  Save this article

Exploring the Association between Oxygen Concentration and Life Expectancy in China: A Quantitative Analysis

Author

Listed:
  • Qing Zou

    (Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China)

  • Yingsi Lai

    (Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
    Sun Yat-Sen Global Health Institute, Sun Yat-Sen University, Guangzhou 510080, China)

  • Zhao-Rong Lun

    (State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China)

Abstract

The aim of this study was to investigate and quantify the association between oxygen concentration and life expectancy. The data from 34 provinces and 39 municipalities were included in all analyses. Bayesian regression modeling with spatial-specific random effects was used to quantify the impact of oxygen concentration (measured as partial pressure of oxygen) on life expectancy, adjusting for other potential confounding factors. We used hierarchical cluster analysis to group the provinces according to disease burden and analyzed the oxygen levels and the characteristics of causes of death between the clusters. The Bayesian regression analysis showed that the life expectancy at the provincial level increased by 0.15 (95% CI: 0.10–0.19) years, while at the municipal level, it increased by 0.17 (95% CI: 0.12–0.22) years, with each additional unit (mmHg) of oxygen concentration, after controlling for potential confounding factors. Three clusters were identified in the hierarchical cluster analysis, which were characterized by different oxygen concentrations, and the years of life lost from causes potentially related to hypoxia were statistically significantly different between the clusters. A positive correlation was found between oxygen concentration and life expectancy in China. The differences in causes of death and oxygen levels in the provincial clusters suggested that oxygen concentration may be an important factor in life expectancy when mediated by diseases that are potentially related to hypoxia.

Suggested Citation

  • Qing Zou & Yingsi Lai & Zhao-Rong Lun, 2023. "Exploring the Association between Oxygen Concentration and Life Expectancy in China: A Quantitative Analysis," IJERPH, MDPI, vol. 20(2), pages 1-13, January.
  • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1125-:d:1029074
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/2/1125/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/20/2/1125/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Daquan Huang & Shuimiao Yang & Tao Liu, 2020. "Life Expectancy in Chinese Cities: Spatially Varied Role of Socioeconomic Development, Population Structure, and Natural Conditions," IJERPH, MDPI, vol. 17(18), pages 1-24, September.
    2. Joshua Goldstein & Thomas Cassidy, 2012. "How slowing senescence translates into longer life expectancy," Population Studies, Taylor & Francis Journals, vol. 66(1), pages 29-37.
    3. Chun Guo & Jianfeng Xu & Mingnian Wang & Tao Yan & Lu Yang & Zhitao Sun, 2015. "Study on Oxygen Supply Standard for Physical Health of Construction Personnel of High-Altitude Tunnels," IJERPH, MDPI, vol. 13(1), pages 1-13, December.
    4. Judith Campisi & Pankaj Kapahi & Gordon J. Lithgow & Simon Melov & John C. Newman & Eric Verdin, 2019. "From discoveries in ageing research to therapeutics for healthy ageing," Nature, Nature, vol. 571(7764), pages 183-192, July.
    5. Yulin Shi & Songqing Fan & Mengge Wu & Zhixiang Zuo & Xingyang Li & Liping Jiang & Qiushuo Shen & Peifang Xu & Lin Zeng & Yongchun Zhou & Yunchao Huang & Zuozhang Yang & Jumin Zhou & Jing Gao & Hu Zho, 2019. "YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Tomasz Wrycza & Annette Baudisch, 2012. "How life expectancy varies with perturbations in age-specific mortality," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 27(13), pages 365-376.
    2. Scott, Andrew J., 2023. "The economics of longevity – An introduction," The Journal of the Economics of Ageing, Elsevier, vol. 24(C).
    3. Sri Hasnawati & Mustofa Usman & Ahmad Faisol & Faiz A. M. Elfaki, 2023. "Analysis and Modeling Gross Domestic Product, Carbon Dioxide Emission, Population Growth, and Life Expectancy at Birth: Case Study in Qatar," International Journal of Energy Economics and Policy, Econjournals, vol. 13(2), pages 467-483, March.
    4. Andrew Fenelon, 2013. "An examination of black/white differences in the rate of age-related mortality increase," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 29(17), pages 441-472.
    5. Seoyeon Lee & Mohammad Naimul Islam & Kaveh Boostanpour & Dvir Aran & Guangchun Jin & Stephanie Christenson & Michael A. Matthay & Walter L. Eckalbar & Daryle J. DePianto & Joseph R. Arron & Liam Mage, 2021. "Molecular programs of fibrotic change in aging human lung," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
    6. Damien S. E. Broekharst & Sjaak Bloem & Marije Blok & Mariët Raatgever & Nathascha Hanzen & Jasmien J. E. de Vette, 2023. "Determining the Appropriate Support for Older Adults with Different Levels of Vitality and Health-Related Quality of Life: An Explanatory Study," IJERPH, MDPI, vol. 20(11), pages 1-11, June.
    7. Xueqing Wang & Quanlong Jiang & Hongdao Zhang & Zhidong He & Yuanyuan Song & Yifan Chen & Na Tang & Yifei Zhou & Yiping Li & Adam Antebi & Ligang Wu & Jing-Dong J. Han & Yidong Shen, 2024. "Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    8. Naina Bhatia-Dey & Thomas Heinbockel, 2021. "The Olfactory System as Marker of Neurodegeneration in Aging, Neurological and Neuropsychiatric Disorders," IJERPH, MDPI, vol. 18(13), pages 1-15, June.
    9. Zhiheng Chen & Yuting Ma & Junyi Hua & Yuanhong Wang & Hongpeng Guo, 2021. "Impacts from Economic Development and Environmental Factors on Life Expectancy: A Comparative Study Based on Data from Both Developed and Developing Countries from 2004 to 2016," IJERPH, MDPI, vol. 18(16), pages 1-18, August.
    10. Takayoshi Sasako & Toshihiro Umehara & Kotaro Soeda & Kazuma Kaneko & Miho Suzuki & Naoki Kobayashi & Yukiko Okazaki & Miwa Tamura-Nakano & Tomoki Chiba & Domenico Accili & C. Ronald Kahn & Tetsuo Nod, 2022. "Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    11. Betz, Ulrich A.K. & Arora, Loukik & Assal, Reem A. & Azevedo, Hatylas & Baldwin, Jeremy & Becker, Michael S. & Bostock, Stefan & Cheng, Vinton & Egle, Tobias & Ferrari, Nicola & Schneider-Futschik, El, 2023. "Game changers in science and technology - now and beyond," Technological Forecasting and Social Change, Elsevier, vol. 193(C).
    12. Christina Bohk-Ewald & Marcus Ebeling & Roland Rau, 2017. "Lifespan Disparity as an Additional Indicator for Evaluating Mortality Forecasts," Demography, Springer;Population Association of America (PAA), vol. 54(4), pages 1559-1577, August.
    13. Old, Jonathan & Scott, Andrew, 2023. "Healthy ageing trends in England between 2002 to 2018: Improving but slowing and unequal," Department of Economics, Working Paper Series qt759110mx, Department of Economics, Institute for Business and Economic Research, UC Berkeley.
    14. Zijun Li & Rongrong Li & Yu Xu & Yuanyuan Xu, 2020. "Study on the Oxygen Enrichment Effect of Individual Oxygen-Supply Device in a Tunnel of Plateau Mine," IJERPH, MDPI, vol. 17(16), pages 1-16, August.
    15. Jinjie Duan & Wenhui Dong & Guangyan Wang & Wenjing Xiu & Guangyin Pu & Jingwen Xu & Chenji Ye & Xu Zhang & Yi Zhu & Chunjiong Wang, 2023. "Senescence-associated 13-HODE production promotes age-related liver steatosis by directly inhibiting catalase activity," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    16. Jin-Li Hu & Min-Yueh Chuang & Shang-Ho Yeh, 2023. "A Dynamic DEA Analysis of Health Output Efficiencies of Cities and Counties in Taiwan," IJERPH, MDPI, vol. 20(6), pages 1-12, March.
    17. Rupesh S. Patel & Rodrigo Romero & Emma V. Watson & Anthony C. Liang & Megan Burger & Peter M. K. Westcott & Kim L. Mercer & Roderick T. Bronson & Eric C. Wooten & Arjun Bhutkar & Tyler Jacks & Stephe, 2022. "A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    18. Cox, Lynne S., 2022. "Therapeutic approaches to treat and prevent age-related diseases through understanding the underlying biological drivers of ageing," The Journal of the Economics of Ageing, Elsevier, vol. 23(C).
    19. Zi Wang & Lina Zou & Yiyan Zhang & Mengnan Zhu & Shuxian Zhang & Di Wu & Jianfeng Lan & Xiao Zang & Qi Wang & Hanxin Zhang & Zixing Wu & Huanhu Zhu & Di Chen, 2023. "ACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    20. Hina Kosakamoto & Fumiaki Obata & Junpei Kuraishi & Hide Aikawa & Rina Okada & Joshua N. Johnstone & Taro Onuma & Matthew D. W. Piper & Masayuki Miura, 2023. "Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila," Nature Communications, Nature, vol. 14(1), pages 1-16, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1125-:d:1029074. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.