Likelihood ratio tests for genetic linkage
Mixtures of binomial distributions are used to model linkage between genes and markers. In several classical models, we study the likelihood ratio test for linkage, which are homogeneity tests in mixture models. Using ad hoc reparametrizations, we prove that the corresponding test statistics converge to the supremum of squared truncated Gaussian processes under the null hypothesis.
Volume (Year): 33 (1997)
Issue (Month): 1 (April)
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