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Modeling strategies in longitudinal data analysis: Covariate, variance function and correlation structure selection

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  • Wang, You-Gan
  • Hin, Lin-Yee

Abstract

A modeling paradigm is proposed for covariate, variance and working correlation structure selection for longitudinal data analysis. Appropriate selection of covariates is pertinent to correct variance modeling and selecting the appropriate covariates and variance function is vital to correlation structure selection. This leads to a stepwise model selection procedure that deploys a combination of different model selection criteria. Although these criteria find a common theoretical root based on approximating the Kullback-Leibler distance, they are designed to address different aspects of model selection and have different merits and limitations. For example, the extended quasi-likelihood information criterion (EQIC) with a covariance penalty performs well for covariate selection even when the working variance function is misspecified, but EQIC contains little information on correlation structures. The proposed model selection strategies are outlined and a Monte Carlo assessment of their finite sample properties is reported. Two longitudinal studies are used for illustration.

Suggested Citation

  • Wang, You-Gan & Hin, Lin-Yee, 2010. "Modeling strategies in longitudinal data analysis: Covariate, variance function and correlation structure selection," Computational Statistics & Data Analysis, Elsevier, vol. 54(12), pages 3359-3370, December.
  • Handle: RePEc:eee:csdana:v:54:y:2010:i:12:p:3359-3370
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    References listed on IDEAS

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    1. Eva Cantoni & Joanna Mills Flemming & Elvezio Ronchetti, 2005. "Variable Selection for Marginal Longitudinal Generalized Linear Models," Biometrics, The International Biometric Society, vol. 61(2), pages 507-514, June.
    2. You-Gan Wang, 2003. "Working correlation structure misspecification, estimation and covariate design: Implications for generalised estimating equations performance," Biometrika, Biometrika Trust, vol. 90(1), pages 29-41, March.
    3. James Cui, 2007. "QIC program and model selection in GEE analyses," Stata Journal, StataCorp LP, vol. 7(2), pages 209-220, June.
    4. Bradley Efron, 2004. "The Estimation of Prediction Error: Covariance Penalties and Cross-Validation," Journal of the American Statistical Association, American Statistical Association, vol. 99, pages 619-632, January.
    5. You-Gan Wang & Xu Lin, 2005. "Effects of Variance-Function Misspecification in Analysis of Longitudinal Data," Biometrics, The International Biometric Society, vol. 61(2), pages 413-421, June.
    6. N. Rao Chaganty & Harry Joe, 2004. "Efficiency of generalized estimating equations for binary responses," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 66(4), pages 851-860, November.
    7. Hin, Lin-Yee & Carey, Vincent J. & Wang, You-Gan, 2007. "Criteria for WorkingCorrelationStructure Selection in GEE: Assessment via Simulation," The American Statistician, American Statistical Association, vol. 61, pages 360-364, November.
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    Cited by:

    1. Zhang, Qiang & Ip, Edward H. & Pan, Junhao & Plemmons, Robert, 2017. "Individual-specific, sparse inverse covariance estimation in generalized estimating equations," Statistics & Probability Letters, Elsevier, vol. 122(C), pages 96-103.
    2. Li, Yang & Zhao, Hui & Sun, Jianguo & Kim, KyungMann, 2014. "Nonparametric tests for panel count data with unequal observation processes," Computational Statistics & Data Analysis, Elsevier, vol. 73(C), pages 103-111.
    3. Xu, Jianwen & Wang, You-Gan, 2014. "Intra-cluster correlation structure in longitudinal data analysis: Selection criteria and misspecification tests," Computational Statistics & Data Analysis, Elsevier, vol. 80(C), pages 70-77.
    4. Kari R. Hart & Teng Fei & John J. Hanfelt, 2021. "Scalable and robust latent trajectory class analysis using artificial likelihood," Biometrics, The International Biometric Society, vol. 77(3), pages 1118-1128, September.
    5. Liya Fu & Yangyang Hao & You-Gan Wang, 2018. "Working correlation structure selection in generalized estimating equations," Computational Statistics, Springer, vol. 33(2), pages 983-996, June.

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