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Impulsive effects on fractional order time delayed gene regulatory networks: Asymptotic stability analysis

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  • Arjunan, Mani Mallika
  • Abdeljawad, Thabet
  • Anbalagan, Pratap

Abstract

This paper address the fractional-order gene regulatory networks (FOGRNs) with both time delays and impulsive effects. Inspired by the integer-order gene regulatory network models, a general class of fractional-order gene regulatory network model is further investigated via fractional-order Lyapunov-Razumikhin stability theory. Firstly, impulsive effects, feedback regulation, and translation time delays are taken well into account and effective analysis techniques are used to reflect the system’s practically dynamic behavior. Secondly, the existence and uniqueness of the equilibrium point of the fractional-order gene regulatory networks are derived based on the Banach contraction mapping principle. Besides, we derived analytically the condition under which the solution of this network is bounded through generalized Gronwall inequality. Thirdly, some novel delay-free sufficient conditions are derived to ensure the global asymptotic stability of the considered model with the help of the fractional-order Lyapunov-Razumikhin method and properties of Mittag-Leffler functions. Finally, an example with numerical simulation is provided to illustrate the validity and effectiveness of the proposed results.

Suggested Citation

  • Arjunan, Mani Mallika & Abdeljawad, Thabet & Anbalagan, Pratap, 2022. "Impulsive effects on fractional order time delayed gene regulatory networks: Asymptotic stability analysis," Chaos, Solitons & Fractals, Elsevier, vol. 154(C).
  • Handle: RePEc:eee:chsofr:v:154:y:2022:i:c:s0960077921009887
    DOI: 10.1016/j.chaos.2021.111634
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    References listed on IDEAS

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    1. Attila Becskei & Luis Serrano, 2000. "Engineering stability in gene networks by autoregulation," Nature, Nature, vol. 405(6786), pages 590-593, June.
    2. Zhaohua Wu & Zhiming Wang & Tiejun Zhou, 2020. "Finite-Time Stability of Fractional-Order Time-Varying Delays Gene Regulatory Networks with Structured Uncertainties and Controllers," Complexity, Hindawi, vol. 2020, pages 1-19, August.
    3. Huang, Chengdai & Cao, Jinde & Xiao, Min, 2016. "Hybrid control on bifurcation for a delayed fractional gene regulatory network," Chaos, Solitons & Fractals, Elsevier, vol. 87(C), pages 19-29.
    4. Wang, JinRong & Ibrahim, Ahmed Gamal & Fečkan, Michal, 2015. "Nonlocal impulsive fractional differential inclusions with fractional sectorial operators on Banach spaces," Applied Mathematics and Computation, Elsevier, vol. 257(C), pages 103-118.
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    Cited by:

    1. Chen, Shenglong & Yang, Jikai & Li, Zhiming & Li, Hong-Li & Hu, Cheng, 2023. "New results for dynamical analysis of fractional-order gene regulatory networks with time delay and uncertain parameters," Chaos, Solitons & Fractals, Elsevier, vol. 175(P1).
    2. Bahrampour, Elham & Asemani, Mohammad Hassan & Dehghani, Maryam, 2023. "Robust global synchronization of delayed incommensurate fractional-order gene regulatory networks," Chaos, Solitons & Fractals, Elsevier, vol. 172(C).

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