IDEAS home Printed from https://ideas.repec.org/a/eee/agiwat/v206y2018icp42-47.html
   My bibliography  Save this article

Absorption of carbamazepine and diclofenac in hydroponically cultivated lettuces and human health risk assessment

Author

Listed:
  • González García, Mariano
  • Fernández-López, Carmen
  • Pedrero-Salcedo, Francisco
  • Alarcón, Juan Jose

Abstract

Due to current water shortages, the use of water from wastewater treatment plants (WWTPs) for horticultural crop irrigation is becoming increasingly common. This practice implies the risk of introducing pharmaceutical compounds into the food chain. The main aim of this work was to study the accumulation of two drugs in lettuces and their subsequent transfer into the food chain. The study focused on two widely used drugs, the anticonvulsant carbamazepine (CBZ) and the anti-inflammatory diclofenac (DCF), with different physicochemical properties in terms of their hydrophobicity and solubility in water. Three varieties of lettuce were selected and irrigated with water containing a mixture of the two pharmaceutical compounds at different concentrations. The results show the leaves presented the highest levels of uptake and greatest bioconcentration factors in the case of CBZ; however, in the case of DCF, by contrast, the highest uptake levels and greatest bioconcentration factors were observed in the roots. For CBZ, the Cleaf/Croot ratio was greater than 1, indicating good root-to-leaf drug translocation, whereas all Cleaf/Croot ratios were less than 1 for DCF. From the data acquired, our evaluation suggests that the concentrations of CBZ and DCF detected in the edible part of the lettuces do not imply any risk to human health.

Suggested Citation

  • González García, Mariano & Fernández-López, Carmen & Pedrero-Salcedo, Francisco & Alarcón, Juan Jose, 2018. "Absorption of carbamazepine and diclofenac in hydroponically cultivated lettuces and human health risk assessment," Agricultural Water Management, Elsevier, vol. 206(C), pages 42-47.
    • Handle: RePEc:eee:agiwat:v:206:y:2018:i:c:p:42-47
    DOI: 10.1016/j.agwat.2018.04.018
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0378377418303883
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.agwat.2018.04.018?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Pedrero, Francisco & Kalavrouziotis, Ioannis & Alarcón, Juan José & Koukoulakis, Prodromos & Asano, Takashi, 2010. "Use of treated municipal wastewater in irrigated agriculture--Review of some practices in Spain and Greece," Agricultural Water Management, Elsevier, vol. 97(9), pages 1233-1241, September.
    2. Elgallal, M. & Fletcher, L. & Evans, B., 2016. "Assessment of potential risks associated with chemicals in wastewater used for irrigation in arid and semiarid zones: A review," Agricultural Water Management, Elsevier, vol. 177(C), pages 419-431.
    3. Libutti, Angela & Gatta, Giuseppe & Gagliardi, Anna & Vergine, Pompilio & Pollice, Alfieri & Beneduce, Luciano & Disciglio, Grazia & Tarantino, Emanuele, 2018. "Agro-industrial wastewater reuse for irrigation of a vegetable crop succession under Mediterranean conditions," Agricultural Water Management, Elsevier, vol. 196(C), pages 1-14.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Mohineeta Pandey & Astha Tirkey & Ankesh Tiwari & Sang Soo Lee & Rashmi Dubey & Ki Hyun Kim & Sudhir Kumar Pandey, 2022. "The Environmental Significance of Contaminants of Concern in the Soil–Vegetable Interface: Sources, Accumulation, Health Risks, and Mitigation through Biochar," Sustainability, MDPI, vol. 14(21), pages 1-23, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Feder, Frédéric, 2021. "Irrigation with treated wastewater in humid regions: Effects on Nitisols, sugarcane yield and quality," Agricultural Water Management, Elsevier, vol. 247(C).
    2. Jemal Fito & Stijn W. H. Hulle, 2021. "Wastewater reclamation and reuse potentials in agriculture: towards environmental sustainability," Environment, Development and Sustainability: A Multidisciplinary Approach to the Theory and Practice of Sustainable Development, Springer, vol. 23(3), pages 2949-2972, March.
    3. Nicoleta Ungureanu & Valentin Vlăduț & Gheorghe Voicu, 2020. "Water Scarcity and Wastewater Reuse in Crop Irrigation," Sustainability, MDPI, vol. 12(21), pages 1-18, October.
    4. Pedrero, Francisco & Grattan, S.R. & Ben-Gal, Alon & Vivaldi, Gaetano Alessandro, 2020. "Opportunities for expanding the use of wastewaters for irrigation of olives," Agricultural Water Management, Elsevier, vol. 241(C).
    5. Hashmat, Sherjeel & Shahid, Muhammad & Tanwir, Kashif & Abbas, Saghir & Ali, Qasim & Niazi, Nabeel Khan & Akram, Muhammad Sohail & Saleem, Muhammad Hamzah & Javed, Muhammad Tariq, 2021. "Elucidating distinct oxidative stress management, nutrient acquisition and yield responses of Pisum sativum L. fertigated with diluted and treated wastewater," Agricultural Water Management, Elsevier, vol. 247(C).
    6. Cakmakci, Talip & Sahin, Ustun, 2021. "Improving silage maize productivity using recycled wastewater under different irrigation methods," Agricultural Water Management, Elsevier, vol. 255(C).
    7. Gao, Yang & Shao, Guangcheng & Wu, Shiqing & Xiaojun, Wang & Lu, Jia & Cui, Jintao, 2021. "Changes in soil salinity under treated wastewater irrigation: A meta-analysis," Agricultural Water Management, Elsevier, vol. 255(C).
    8. Echchelh, Alban & Hess, Tim & Sakrabani, Ruben, 2018. "Reusing oil and gas produced water for irrigation of food crops in drylands," Agricultural Water Management, Elsevier, vol. 206(C), pages 124-134.
    9. Musazura, W. & Odindo, A.O. & Tesfamariam, E.H. & Hughes, J.C. & Buckley, C.A., 2019. "Nitrogen and phosphorus dynamics in plants and soil fertigated with decentralised wastewater treatment effluent," Agricultural Water Management, Elsevier, vol. 215(C), pages 55-62.
    10. Chojnacka, K. & Witek-Krowiak, A. & Moustakas, K. & Skrzypczak, D. & Mikula, K. & Loizidou, M., 2020. "A transition from conventional irrigation to fertigation with reclaimed wastewater: Prospects and challenges," Renewable and Sustainable Energy Reviews, Elsevier, vol. 130(C).
    11. Rossetto, Rudy & De Filippis, Giovanna & Triana, Federico & Ghetta, Matteo & Borsi, Iacopo & Schmid, Wolfgang, 2019. "Software tools for management of conjunctive use of surface- and ground-water in the rural environment: integration of the Farm Process and the Crop Growth Module in the FREEWAT platform," Agricultural Water Management, Elsevier, vol. 223(C), pages 1-1.
    12. Azunre, Gideon Abagna & Amponsah, Owusu & Takyi, Stephen Appiah & Mensah, Henry & Braimah, Imoro, 2022. "Urban informalities in sub-Saharan Africa (SSA): A solution for or barrier against sustainable city development," World Development, Elsevier, vol. 152(C).
    13. Vasileios A. Tzanakakis & Andrea G. Capodaglio & Andreas N. Angelakis, 2023. "Insights into Global Water Reuse Opportunities," Sustainability, MDPI, vol. 15(17), pages 1-30, August.
    14. Ejovi Akpojevwe Abafe & Yonas T. Bahta & Henry Jordaan, 2022. "Exploring Biblioshiny for Historical Assessment of Global Research on Sustainable Use of Water in Agriculture," Sustainability, MDPI, vol. 14(17), pages 1-34, August.
    15. Dimitra Lazaridou & Anastasios Michailidis & Konstantinos Mattas, 2019. "Evaluating the Willingness to Pay for Using Recycled Water for Irrigation," Sustainability, MDPI, vol. 11(19), pages 1-8, September.
    16. Alfredo Valdes Ramos & Elsa N. Aguilera Gonzalez & Gloria Tobón Echeverri & Luis Samaniego Moreno & Lourdes Díaz Jiménez & Salvador Carlos Hernández, 2019. "Potential Uses of Treated Municipal Wastewater in a Semiarid Region of Mexico," Sustainability, MDPI, vol. 11(8), pages 1-23, April.
    17. J. Jed Brown & Probir Das & Mohammad Al-Saidi, 2018. "Sustainable Agriculture in the Arabian/Persian Gulf Region Utilizing Marginal Water Resources: Making the Best of a Bad Situation," Sustainability, MDPI, vol. 10(5), pages 1-16, April.
    18. Andreas N. Angelakis & Mohammad Valipour & Abdelkader T. Ahmed & Vasileios Tzanakakis & Nikolaos V. Paranychianakis & Jens Krasilnikoff & Renato Drusiani & Larry Mays & Fatma El Gohary & Demetris Kout, 2021. "Water Conflicts: From Ancient to Modern Times and in the Future," Sustainability, MDPI, vol. 13(8), pages 1-31, April.
    19. Mabasa, Nyiko C. & Jones, Clifford L.W. & Laing, Mark, 2021. "The use of treated brewery effluent for salt tolerant crop irrigation," Agricultural Water Management, Elsevier, vol. 245(C).
    20. Maestre-Valero, J.F. & Gonzalez-Ortega, M.J. & Martinez-Alvarez, V. & Gallego-Elvira, B. & Conesa-Jodar, F.J. & Martin-Gorriz, B., 2019. "Revaluing the nutrition potential of reclaimed water for irrigation in southeastern Spain," Agricultural Water Management, Elsevier, vol. 218(C), pages 174-181.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:agiwat:v:206:y:2018:i:c:p:42-47. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/agwat .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.