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A covariate-adjusted adaptive design for two-stage clinical trials with survival data


  • Uttam Bandyopadhyay
  • Atanu Biswas
  • Rahul Bhattacharya


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  • Uttam Bandyopadhyay & Atanu Biswas & Rahul Bhattacharya, 2010. "A covariate-adjusted adaptive design for two-stage clinical trials with survival data," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 64(2), pages 202-226.
  • Handle: RePEc:bla:stanee:v:64:y:2010:i:2:p:202-226

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    References listed on IDEAS

    1. Qing Liu & George Y. H. Chi, 2001. "On Sample Size and Inference for Two-Stage Adaptive Designs," Biometrics, The International Biometric Society, vol. 57(1), pages 172-177, March.
    2. Zheng, Gang & Gastwirth, Joseph L., 2001. "On the Fisher information in randomly censored data," Statistics & Probability Letters, Elsevier, vol. 52(4), pages 421-426, May.
    3. Ying Kuen Cheung & Peter F. Thall, 2002. "Monitoring the Rates of Composite Events with Censored Data in Phase II Clinical Trials," Biometrics, The International Biometric Society, vol. 58(1), pages 89-97, March.
    4. Stute, Winfried, 1992. "Strong consistency under the Koziol--Green model," Statistics & Probability Letters, Elsevier, vol. 14(4), pages 313-320, July.
    5. Noel Veraverbeke & Carmen Cadarso-Suárez, 2000. "Estimation of the conditional distribution in a conditional Koziol-green model," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 9(1), pages 97-122, June.
    6. Cheng, Philip E. & Lin, Gwo Dong, 1987. "Maximum likelihood estimation of a survival function under the koziol-green proportional hazards model," Statistics & Probability Letters, Elsevier, vol. 5(1), pages 75-80, January.
    7. J. Ghorai, 1991. "Estimation of a smooth quantile function under the proportional hazards model," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 43(4), pages 747-760, December.
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    Cited by:

    1. Bandyopadhyay, Uttam & Biswas, Atanu, 2016. "Fixed-width confidence interval for two-stage response-adaptive designs in ridit analysis," Statistics & Probability Letters, Elsevier, vol. 108(C), pages 45-51.

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