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A New Dose-Finding Design for Bivariate Outcomes

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  • Anastasia Ivanova

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  • Anastasia Ivanova, 2003. "A New Dose-Finding Design for Bivariate Outcomes," Biometrics, The International Biometric Society, vol. 59(4), pages 1001-1007, December.
    • Handle: RePEc:bla:biomet:v:59:y:2003:i:4:p:1001-1007
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    File URL: http://hdl.handle.net/10.1111/j.0006-341X.2003.00115.x
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    References listed on IDEAS

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    1. Mario Stylianou & Nancy Flournoy, 2002. "Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression," Biometrics, The International Biometric Society, vol. 58(1), pages 171-177, March.
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    Cited by:

    1. Shenghua Fan & Bee Leng Lee & Ying Lu, 2020. "A Curve-Free Bayesian Decision-Theoretic Design for Phase Ia/Ib Trials Considering Both Safety and Efficacy Outcomes," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 12(2), pages 146-166, July.
    2. Nadine Houede & Peter F. Thall & Hoang Nguyen & Xavier Paoletti & Andrew Kramar, 2010. "Utility-Based Optimization of Combination Therapy Using Ordinal Toxicity and Efficacy in Phase I/II Trials," Biometrics, The International Biometric Society, vol. 66(2), pages 532-540, June.
    3. Peter F. Thall & Hoang Q. Nguyen & Elihu H. Estey, 2008. "Patient-Specific Dose Finding Based on Bivariate Outcomes and Covariates," Biometrics, The International Biometric Society, vol. 64(4), pages 1126-1136, December.
    4. Guosheng Yin & Yisheng Li & Yuan Ji, 2006. "Bayesian Dose-Finding in Phase I/II Clinical Trials Using Toxicity and Efficacy Odds Ratios," Biometrics, The International Biometric Society, vol. 62(3), pages 777-787, September.
    5. Anastasia Ivanova & Se Hee Kim, 2009. "Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach," Biometrics, The International Biometric Society, vol. 65(1), pages 307-315, March.
    6. Sergei Leonov & Bahjat Qaqish, 2020. "Correlated endpoints: simulation, modeling, and extreme correlations," Statistical Papers, Springer, vol. 61(2), pages 741-766, April.
    7. Yinghui Zhou & John Whitehead & Pasi Korhonen & Mika Mustonen, 2008. "Implementation of a Bayesian Design in a Dose-Escalation Study of an Experimental Agent in Healthy Volunteers," Biometrics, The International Biometric Society, vol. 64(1), pages 299-308, March.
    8. Peter F. Thall & Aniko Szabo & Hoang Q. Nguyen & Catherine M. Amlie-Lefond & Osama O. Zaidat, 2011. "Optimizing the Concentration and Bolus of a Drug Delivered by Continuous Infusion," Biometrics, The International Biometric Society, vol. 67(4), pages 1638-1646, December.

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