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A Curve-Free Method for Phase I Clinical Trials

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  • Mauro Gasparini
  • Jeffrey Eisele

Abstract

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  • Mauro Gasparini & Jeffrey Eisele, 2000. "A Curve-Free Method for Phase I Clinical Trials," Biometrics, The International Biometric Society, vol. 56(2), pages 609-615, June.
    • Handle: RePEc:bla:biomet:v:56:y:2000:i:2:p:609-615
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    File URL: http://hdl.handle.net/10.1111/j.0006-341X.2000.00609.x
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    References listed on IDEAS

    as
    1. Tang, Jen & Gupta, A. K., 1984. "On the distribution of the product of independent beta random variables," Statistics & Probability Letters, Elsevier, vol. 2(3), pages 165-168, May.
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    Cited by:

    1. Drovandi, Christopher C. & McGree, James M. & Pettitt, Anthony N., 2013. "Sequential Monte Carlo for Bayesian sequentially designed experiments for discrete data," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 320-335.
    2. Mezzetti, Maura & Muliere, Pietro & Bulla, Paolo, 2007. "An application of reinforced urn processes to determining maximum tolerated dose," Statistics & Probability Letters, Elsevier, vol. 77(7), pages 740-747, April.
    3. Ying Kuen Cheung, 2002. "On the Use of Nonparametric Curves in Phase I Trials with Low Toxicity Tolerance," Biometrics, The International Biometric Society, vol. 58(1), pages 237-240, March.
    4. Guosheng Yin & Ying Yuan, 2009. "Bayesian dose finding in oncology for drug combinations by copula regression," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 58(2), pages 211-224, May.
    5. John O'Quigley, 2002. "Curve-Free and Model-Based Continual Reassessment Method Designs," Biometrics, The International Biometric Society, vol. 58(1), pages 245-249, March.
    6. Tian, Guo-Liang & Ng, Kai Wang & Tan, Ming, 2008. "EM-type algorithms for computing restricted MLEs in multivariate normal distributions and multivariate t-distributions," Computational Statistics & Data Analysis, Elsevier, vol. 52(10), pages 4768-4778, June.
    7. Paoletti, Xavier & O'Quigley, John & Maccario, Jean, 2004. "Design efficiency in dose finding studies," Computational Statistics & Data Analysis, Elsevier, vol. 45(2), pages 197-214, March.
    8. Guosheng Yin & Yisheng Li & Yuan Ji, 2006. "Bayesian Dose-Finding in Phase I/II Clinical Trials Using Toxicity and Efficacy Odds Ratios," Biometrics, The International Biometric Society, vol. 62(3), pages 777-787, September.
    9. Ying Kuen Cheung & Rick Chappell, 2002. "A Simple Technique to Evaluate Model Sensitivity in the Continual Reassessment Method," Biometrics, The International Biometric Society, vol. 58(3), pages 671-674, September.
    10. Ying Yuan & Guosheng Yin, 2009. "Bayesian dose finding by jointly modelling toxicity and efficacy as time‐to‐event outcomes," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 58(5), pages 719-736, December.
    11. Linda M. Haines & Inna Perevozskaya & William F. Rosenberger, 2003. "Bayesian Optimal Designs for Phase I Clinical Trials," Biometrics, The International Biometric Society, vol. 59(3), pages 591-600, September.
    12. Peter F. Thall & Hoang Q. Nguyen & Ralph G. Zinner, 2017. "Parametric dose standardization for optimizing two-agent combinations in a phase I–II trial with ordinal outcomes," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 66(1), pages 201-224, January.
    13. Guosheng Yin & Ying Yuan, 2009. "A Latent Contingency Table Approach to Dose Finding for Combinations of Two Agents," Biometrics, The International Biometric Society, vol. 65(3), pages 866-875, September.

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