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Determinants of increased opioid-related mortality in the united states and canada, 1990-2013: A systematic review

Author

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  • King, N.B.
  • Fraser, V.
  • Boikos, C.
  • Richardson, R.
  • Harper, S.

Abstract

We review evidence of determinants contributing to increased opioid-related mortality in the United States and Canada between 1990 and 2013. We identified 17 determinants of opioid-relatedmortality andmortality increases that we classified into 3 categories: prescriber behavior, user behavior and characteristics, and environmental and systemic determinants. These determinants operate independently but interact in complex ways that vary according to geography and population,making generalization from single studies inadvisable. Researchers in this area face significant methodological difficulties; most of the studies in our review were ecological or observational and lacked control groups or adjustment for confounding factors; thus, causal inferences are difficult. Preventing additional opioid-related mortality will likely require interventions that address multiple determinants and are tailored to specific locations and populations.

Suggested Citation

  • King, N.B. & Fraser, V. & Boikos, C. & Richardson, R. & Harper, S., 2014. "Determinants of increased opioid-related mortality in the united states and canada, 1990-2013: A systematic review," American Journal of Public Health, American Public Health Association, vol. 104(8), pages 32-42.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2014.301966_9
    DOI: 10.2105/AJPH.2014.301966
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    Cited by:

    1. Lucas Marín Llanes & Hernando Zuleta, 2022. "Myths of drug consumption decriminalization: effects of Portuguese decriminalization on violent and drug use mortality," Documentos CEDE 20328, Universidad de los Andes, Facultad de Economía, CEDE.
    2. Bardwell, Geoff & Small, Will & Lavalley, Jennifer & McNeil, Ryan & Kerr, Thomas, 2021. "“People need them or else they're going to take fentanyl and die”: A qualitative study examining the ‘problem’ of prescription opioid diversion during an overdose epidemic," Social Science & Medicine, Elsevier, vol. 279(C).
    3. Justin C Yang & Andres Roman-Urrestarazu & Carol Brayne, 2019. "Differences in receipt of opioid agonist treatment and time to enter treatment for opioid use disorder among specialty addiction programs in the United States, 2014-17," PLOS ONE, Public Library of Science, vol. 14(12), pages 1-16, December.
    4. Sucharita Gopal & Manfred M. Fischer, 2023. "Opioid mortality in the US: quantifying the direct and indirect impact of sociodemographic and socioeconomic factors," Letters in Spatial and Resource Sciences, Springer, vol. 16(1), pages 1-17, December.
    5. Ibrahima Bocoum & Aurelas B. Tohon & Roger Rukundo & Catherine Macombe & Jean-Pierre Revéret, 2019. "Effect of Income Inequality on Health in Quebec: New Insights from Panel Data," Sustainability, MDPI, vol. 11(20), pages 1-17, October.
    6. Anna Persmark & Maria Wemrell & Sofia Zettermark & George Leckie & S V Subramanian & Juan Merlo, 2019. "Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)," PLOS ONE, Public Library of Science, vol. 14(8), pages 1-21, August.
    7. Benjamin R. Brady & Ehmer A. Taj & Elena Cameron & Aaron M. Yoder & Jennifer S. De La Rosa, 2023. "A Diagram of the Social-Ecological Conditions of Opioid Misuse and Overdose," IJERPH, MDPI, vol. 20(20), pages 1-19, October.
    8. Fiona Webster & Kathleen Rice & Joel Katz & Onil Bhattacharyya & Craig Dale & Ross Upshur, 2019. "An ethnography of chronic pain management in primary care: The social organization of physicians’ work in the midst of the opioid crisis," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-16, May.

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