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Avasimibe and Sirt 1 Activators Reverse NAFLD and Obesity

Author

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  • Ian James Martins

    (Centre of Excellence in Alzheimer’s disease Research and Care, School of Medical Sciences, Edith Cowan University, Australia
    School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Australia
    Medical Centre, McCusker Alzheimer’s Research Foundation, Australia)

Abstract

In epidemiological studies human obesity is clearly associated with the increased risk for atherosclerosis contributing to the early onset of coronary artery disease and diabetes. Visceral obesity in particular increases the risk of atherosclerosis owing to both insulin resistance and dyslipoproteinemia. Risk factors for atherosclerosis that could be exacerbated by obesity include hypertension and hyper lipidemia particularly hyper triglyceridemia which are risk factors for Alzheimer’s disease. The susceptibility of humans to obesity is far higher compared with other species and in man favours the deposition of fat [1].

Suggested Citation

  • Ian James Martins, 2017. "Avasimibe and Sirt 1 Activators Reverse NAFLD and Obesity," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(3), pages 38-39, May.
    • Handle: RePEc:adp:jnapdd:v:1:y:2017:i:3:p:38-39
    DOI: 10.19080/NAPDD.2017.01.555561
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    Cited by:

    1. Ian James Martins, 2018. "Indian Spices and Unhealthy Diets interfere with Drug Therapy in Diabetes and Neurodegenerative Diseases," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 3(4), pages 73-76, January.

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