A test of the predictive validity of non-linear QALY models using time trade-off utilities
AbstractThis paper presents a test of the predictive validity of various classes of QALY models (i.e., linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO-based QALY calculations may be biased. This bias can be avoided using a power QALY model.
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Bibliographic InfoPaper provided by Department of Economics and Business, Universitat Pompeu Fabra in its series Economics Working Papers with number 741.
Date of creation: Feb 2004
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Cost-utility analysis; QALYs; power QALY model; predictive validity; time tradeoff; Leex;
Find related papers by JEL classification:
- I10 - Health, Education, and Welfare - - Health - - - General
- D99 - Microeconomics - - Intertemporal Choice and Growth - - - Other
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