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The EQ-5D-5L Valuation Study in Egypt

Author

Listed:
  • Sahar Al Shabasy

    (Cairo University)

  • Maggie Abbassi

    (Cairo University)

  • Aureliano Finch

    (EuroQol Group Office)

  • Bram Roudijk

    (EuroQol Group Office)

  • Darrin Baines

    (Initiate Consultancy)

  • Samar Farid

    (Cairo University)

Abstract

Introduction No value sets exist for either the EQ-5D-3L or the EQ-5D-5L in Egypt, despite local pharmacoeconomic guidelines recommending the use of the EQ-5D to derive utility. Most published Egyptian economic evaluation studies have used utility values from other published studies and systematic reviews. Objective Our objective was to develop an Egyptian EQ-5D-5L value set using the international EuroQol standardized protocol (EQ-VT-2.1). This study is a revision of a previous EQ-5D-5L value set for Egypt retracted by the authors. Methods Adult Egyptian participants were recruited from public places using multi-stratified quota sampling based on age, sex, and geographical distribution. Two elicitation techniques were applied: the composite time trade-off (cTTO) and discrete-choice experiments (DCEs). Before actual data collection, interviewers’ performance was assessed in a pilot phase. Data were modelled using generalized least squares, Tobit, heteroskedastic, logit, and hybrid models, and the best fitting model was selected based on logical consistency of the parameters, significance level, prediction accuracy, and model parsimony. Results A total of 1378 interviews were conducted, of which 188 were excluded because they were incomplete and did not comply with the protocol, 216 were pilot interviews, and 974 were included in the final analysis. The heteroskedastic model with constraints (model 4) based on the cTTO data was selected as the preferred model to generate the value set. Values ranged from − 0.964 for the worst health state (55555) to 1 for full health (11111) and 0.948 for 11211, with 1123 of all predicted health states (35.94%) being worse than dead. Mobility had the largest impact on health state preference values. Conclusion This is the first value set for the EQ-5D-5L based on social preferences obtained from a nationally representative sample in Egypt or any Arabic-speaking country. The value set can be used as a scoring system for economic evaluation and to improve the quality of health technology assessment in the Egyptian healthcare system.

Suggested Citation

  • Sahar Al Shabasy & Maggie Abbassi & Aureliano Finch & Bram Roudijk & Darrin Baines & Samar Farid, 2022. "The EQ-5D-5L Valuation Study in Egypt," PharmacoEconomics, Springer, vol. 40(4), pages 433-447, April.
    • Handle: RePEc:spr:pharme:v:40:y:2022:i:4:d:10.1007_s40273-021-01100-y
    DOI: 10.1007/s40273-021-01100-y
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    References listed on IDEAS

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    1. Manal H. El-Hamamsy & Gihan H. Elsisi & Randa Eldessouki & Mohamed M. Elmazar & Ahmed S. Taha & Basma F. Awad & Hossam Elmansy, 2016. "Economic Evaluation of the Combined Use of Warfarin and Low-dose Aspirin Versus Warfarin Alone in Mechanical Valve Prostheses," Applied Health Economics and Health Policy, Springer, vol. 14(4), pages 431-440, August.
    2. Emily Lancsar & Jordan Louviere, 2006. "Deleting ‘irrational’ responses from discrete choice experiments: a case of investigating or imposing preferences?," Health Economics, John Wiley & Sons, Ltd., vol. 15(8), pages 797-811, August.
    3. Bram Roudijk & A. Rogier T. Donders & Peep F. M. Stalmeier, 2019. "Cultural Values: Can They Explain Differences in Health Utilities between Countries?," Medical Decision Making, , vol. 39(5), pages 605-616, July.
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