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Regulatory dependence and Scientific Advisory Boards

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  • Chok, Jay Inghwee
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    Abstract

    The Food and Drug Administration (FDA) uses scientific procedures to evaluate regulated firms' new product applications. Much of its basic intellectual resources, in the form of scientific advisory committee members, come from research institutions. Regulated firms may seek connections to the FDA advisory committee members to affect the regulatory approval process. However, individual linkages may fail. The use of Scientific Advisory Boards (SAB) with multiple members provides redundant ties to the regulator, which means that the failure of each tie becomes less material. This paper is principally concerned with the firm's motivation to rebalance power imbalances rather than any actual regulatory outcomes. Controlling for alternative explanations, I find that dependence on the regulator is positively associated with the probability of having a SAB. Selected network diagrams add credibility to the hypothesis.

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    Bibliographic Info

    Article provided by Elsevier in its journal Research Policy.

    Volume (Year): 38 (2009)
    Issue (Month): 5 (June)
    Pages: 710-725

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    Handle: RePEc:eee:respol:v:38:y:2009:i:5:p:710-725

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    Web page: http://www.elsevier.com/locate/respol

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    Keywords: Scientific Advisory Boards Food and drug administration Regulatory dependence;

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    1. Liebeskind, Julia Porter, 1997. "Keeping Organizational Secrets: Protective Institutional Mechanisms and Their Costs," Industrial and Corporate Change, Oxford University Press, vol. 6(3), pages 623-63, September.
    2. Kandel, E. & Lazear, E.P., 1990. "Peer Pressure and Partnerships," Papers 90-07, Rochester, Business - Managerial Economics Research Center.
    3. F. M. Fisher & P. Temin, 1971. "Returns-to-Scale in Research and Development: What Does the Schupeterian Hypothesis Imply?," Working papers 74, Massachusetts Institute of Technology (MIT), Department of Economics.
    4. Jost, Peter-J, 1997. "Monitoring, Appeal, and Investigation: The Enforcement and Legal Process," Journal of Regulatory Economics, Springer, vol. 12(2), pages 127-46, September.
    5. Czarnitzki, Dirk & Glänzel, Wolfgang & Hussinger, Katrin, 2007. "Heterogeneity of Patenting Activity and Its Implications for Scientific Research," ZEW Discussion Papers 07-028, ZEW - Zentrum für Europäische Wirtschaftsforschung / Center for European Economic Research.
    6. Roijakkers, Nadine & Hagedoorn, John, 2006. "Inter-firm R&D partnering in pharmaceutical biotechnology since 1975: Trends, patterns, and networks," Research Policy, Elsevier, vol. 35(3), pages 431-446, April.
    7. Wesley M Cohen & Richard R Nelson & John P Walsh, 2003. "Protecting Their Intellectual Assets: Appropriability Conditions and Why U.S. Manufacturing Firms Patent (Or Not)," Levine's Working Paper Archive 618897000000000624, David K. Levine.
    8. Megginson, William L & Weiss, Kathleen A, 1991. " Venture Capitalist Certification in Initial Public Offerings," Journal of Finance, American Finance Association, vol. 46(3), pages 879-903, July.
    9. Zucker, Lynne G & Darby, Michael R & Brewer, Marilynn B, 1998. "Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises," American Economic Review, American Economic Association, vol. 88(1), pages 290-306, March.
    10. Mansfield, Edwin & Schwartz, Mark & Wagner, Samuel, 1981. "Imitation Costs and Patents: An Empirical Study," Economic Journal, Royal Economic Society, vol. 91(364), pages 907-18, December.
    11. Scott Shane & Daniel Cable, 2002. "Network Ties, Reputation, and the Financing of New Ventures," Management Science, INFORMS, vol. 48(3), pages 364-381, March.
    12. Sampat, Bhaven N., 2006. "Patenting and US academic research in the 20th century: The world before and after Bayh-Dole," Research Policy, Elsevier, vol. 35(6), pages 772-789, July.
    13. Lynne G. Zucker & Michael R. Darby & Jeff S. Armstrong, 2002. "Commercializing Knowledge: University Science, Knowledge Capture, and Firm Performance in Biotechnology," Management Science, INFORMS, vol. 48(1), pages 138-153, January.
    14. Zucker, Lynne G. & Darby, Michael R. & Armstrong, Jeff, 1994. "Inter-Institutional Spillover Effects in the Commercialization of Bioscience," Institute for Social Science Research, Working Paper Series qt4d96f3xh, Institute for Social Science Research, UCLA.
    15. Kim, Jerry W. & Higgins, Monica C., 2007. "Where do alliances come from?: The effects of upper echelons on alliance formation," Research Policy, Elsevier, vol. 36(4), pages 499-514, May.
    16. Stiglitz, Joseph E & Weiss, Andrew, 1981. "Credit Rationing in Markets with Imperfect Information," American Economic Review, American Economic Association, vol. 71(3), pages 393-410, June.
    17. Nelson, Richard R., 2004. "The market economy, and the scientific commons," Research Policy, Elsevier, vol. 33(3), pages 455-471, April.
    18. Louis, Karen Seashore, et al, 2001. " Entrepreneurship, Secrecy, and Productivity: A Comparison of Clinical and Non-clinical Life Sciences Faculty," The Journal of Technology Transfer, Springer, vol. 26(3), pages 233-45, June.
    19. Audretsch, David B & Stephan, Paula E, 1996. "Company-Scientist Locational Links: The Case of Biotechnology," American Economic Review, American Economic Association, vol. 86(3), pages 641-52, June.
    20. Cetindamar, Dilek & Laage-Hellman, Jens, 2003. " Growth Dynamics in the Biomedical/Biotechnology System," Small Business Economics, Springer, vol. 20(4), pages 287-303, June.
    21. Paul Willman & David Coen & David Currie & Martin Siner, 2003. "The evolution of regulatory relationships; regulatory institutions and firm behaviour in privatized industries," Industrial and Corporate Change, Oxford University Press, vol. 12(1), pages 69-89, February.
    22. Ajay Agrawal & Rebecca Henderson, 2002. "Putting Patents in Context: Exploring Knowledge Transfer from MIT," Management Science, INFORMS, vol. 48(1), pages 44-60, January.
    23. Murray, Fiona, 2004. "The role of academic inventors in entrepreneurial firms: sharing the laboratory life," Research Policy, Elsevier, vol. 33(4), pages 643-659, May.
    24. Mary K. Olson, 1997. "Firm Characteristics and the Speed of FDA Approval," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 6(1), pages 377-401, 06.
    25. Spence, A Michael, 1973. "Job Market Signaling," The Quarterly Journal of Economics, MIT Press, vol. 87(3), pages 355-74, August.
    26. Stephan, Paula E & Everhart, Stephen S, 1998. " The Changing Rewards to Science: The Case of Biotechnology," Small Business Economics, Springer, vol. 10(2), pages 141-51, March.
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