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Plasma proteomic associations with genetics and health in the UK Biobank
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- Jing Sun & Yue Liu & Jianhui Zhao & Bin Lu & Siyun Zhou & Wei Lu & Jingsun Wei & Yeting Hu & Xiangxing Kong & Junshun Gao & Hong Guan & Junli Gao & Qian Xiao & Xue Li, 2024. "Plasma proteomic and polygenic profiling improve risk stratification and personalized screening for colorectal cancer," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
- Xuening Zhang & Hao Zhao & Meng Wan & Jinyu Man & Tongchao Zhang & Xiaorong Yang & Ming Lu, 2025. "Associations of 2923 plasma proteins with incident inflammatory bowel disease in a prospective cohort study and genetic analysis," Nature Communications, Nature, vol. 16(1), pages 1-15, December.
- Gianpaolo Zammarchi & Claudia Pisanu, 2025. "Identification of genes shared between sedentary behaviour and inflammation: a bivariate genetic correlation analysis," Computational Statistics, Springer, vol. 40(4), pages 1933-1958, April.
- Yuji Yamamoto & Yuya Shirai & Kyuto Sonehara & Shinichi Namba & Takafumi Ojima & Kenichi Yamamoto & Ryuya Edahiro & Ken Suzuki & Akinori Kanai & Yoshiya Oda & Yutaka Suzuki & Takayuki Morisaki & Akira, 2025. "Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases," Nature Communications, Nature, vol. 16(1), pages 1-18, December.
- Anders Mälarstig & Felix Grassmann & Leo Dahl & Marios Dimitriou & Dianna McLeod & Marike Gabrielson & Karl Smith-Byrne & Cecilia E. Thomas & Tzu-Hsuan Huang & Simon K. G. Forsberg & Per Eriksson & Mi, 2023. "Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
- Keren Papier & Joshua R. Atkins & Tammy Y. N. Tong & Kezia Gaitskell & Trishna Desai & Chibuzor F. Ogamba & Mahboubeh Parsaeian & Gillian K. Reeves & Ian G. Mills & Tim J. Key & Karl Smith-Byrne & Rut, 2024. "Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
- Magdalena Sevilla-González & Kirk Smith & Ningyuan Wang & Aubrey E. Jensen & Elizabeth M. Litkowski & Hyunkyung Kim & Daniel A. DiCorpo & Sarah Hsu & Jinrui Cui & Ching-Ti Liu & Chenglong Yu & John J., 2025. "Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes," Nature Communications, Nature, vol. 16(1), pages 1-12, December.
- Naman S. Shetty & Mokshad Gaonkar & Nirav Patel & Akhil Pampana & Nehal Vekariya & Peng Li & Garima Arora & Pankaj Arora, 2024. "Determinants of transthyretin levels and their association with adverse clinical outcomes among UK Biobank participants," Nature Communications, Nature, vol. 15(1), pages 1-7, December.
- Javier Botey-Bataller & Hedwig D. Vrijmoeth & Jeanine Ursinus & Bart-Jan Kullberg & Cees C. Wijngaard & Hadewych Hofstede & Ahmed Alaswad & Manoj K. Gupta & Lennart M. Roesner & Jochen Huehn & Thomas , 2024. "A comprehensive genetic map of cytokine responses in Lyme borreliosis," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Peng Ren & Xiao-He Hou & Zeyu Li & Jia You & Yuzhu Li & Wei Zhang & Weikang Gong & Bei Zhang & Bangsheng Wu & Linbo Wang & Chun Shen & Yujie Zhao & Qing Ma & Jujiao Kang & Yuchao Jiang & Neil Roberts , 2025. "Atlas of proteomic signatures of brain structure and its links to brain disorders," Nature Communications, Nature, vol. 16(1), pages 1-18, December.
- Robert F. Hillary & Danni A. Gadd & Zhana Kuncheva & Tasos Mangelis & Tinchi Lin & Kyle Ferber & Helen McLaughlin & Heiko Runz & Riccardo E. Marioni & Christopher N. Foley & Benjamin B. Sun, 2024. "Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Jia You & Yu Guo & Yi Zhang & Ju-Jiao Kang & Lin-Bo Wang & Jian-Feng Feng & Wei Cheng & Jin-Tai Yu, 2023. "Plasma proteomic profiles predict individual future health risk," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
- Natalie DeForest & Yuqi Wang & Zhiyi Zhu & Jacqueline S. Dron & Ryan Koesterer & Pradeep Natarajan & Jason Flannick & Tiffany Amariuta & Gina M. Peloso & Amit R. Majithia, 2024. "Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Mauro Tutino & Nancy Yiu-Lin Yu & Konstantinos Hatzikotoulas & Young-Chan Park & Peter Kreitmaier & Georgia Katsoula & Reinhard Berner & Kristina Casteels & Helena Elding Larsson & Olga Kordonouri & M, 2025. "Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes," Nature Communications, Nature, vol. 16(1), pages 1-9, December.
- Joel T. Rämö & Bryan R. Gorman & Lu-Chen Weng & Sean J. Jurgens & Panisa Singhanetr & Marisa G. Tieger & Elon HC Dijk & Christopher W. Halladay & Xin Wang & Blake M. Hauser & Soo Hyun Kim & Joost Brin, 2025. "Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
- Karsten Suhre & Guhan Ram Venkataraman & Harendra Guturu & Anna Halama & Nisha Stephan & Gaurav Thareja & Hina Sarwath & Khatereh Motamedchaboki & Margaret K. R. Donovan & Asim Siddiqui & Serafim Batz, 2024. "Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
- Yash Patel & Jean Shin & Eeva Sliz & Ariana Tang & Aniket Mishra & Rui Xia & Edith Hofer & Hema Sekhar Reddy Rajula & Ruiqi Wang & Frauke Beyer & Katrin Horn & Max Riedl & Jing Yu & Henry Völzke & Rob, 2024. "Genetic risk factors underlying white matter hyperintensities and cortical atrophy," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
- Baihan Wang & Alfred Pozarickij & Mohsen Mazidi & Neil Wright & Pang Yao & Saredo Said & Andri Iona & Christiana Kartsonaki & Hannah Fry & Kuang Lin & Yiping Chen & Huaidong Du & Daniel Avery & Dan Sc, 2025. "Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
- Chirag Krishna & Joshua Chiou & Saori Sakaue & Joyce B. Kang & Stephen M. Christensen & Isac Lee & Melis Atalar Aksit & Hye In Kim & David Schack & Soumya Raychaudhuri & Daniel Ziemek & Xinli Hu, 2024. "The influence of HLA genetic variation on plasma protein expression," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Rikke Linnemann Nielsen & Thomas Monfeuga & Robert R. Kitchen & Line Egerod & Luis G. Leal & August Thomas Hjortshøj Schreyer & Frederik Steensgaard Gade & Carol Sun & Marianne Helenius & Lotte Simons, 2024. "Data-driven identification of predictive risk biomarkers for subgroups of osteoarthritis using interpretable machine learning," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Wenbo Jiang & Hang Wang & Yiding Geng & Meijuan Guo & Yingdong Zuo & Sijia Han & Zijie Liu & Shuaijun Chen & Shuzhen Fan & Shangying Li & Conghui Qiao & Qianzhu Li & Bai Li & Yunpeng Zhang & Wei Wei &, 2025. "The health impacts and genetic architecture of food liking in cardio-metabolic diseases," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Mine Koprulu & Eleanor Wheeler & Nicola D. Kerrison & Spiros Denaxas & Julia Carrasco-Zanini & Chloe M. Orkin & Harry Hemingway & Nicholas J. Wareham & Maik Pietzner & Claudia Langenberg, 2025. "Sex differences in the genetic regulation of the human plasma proteome," Nature Communications, Nature, vol. 16(1), pages 1-10, December.
- Douglas P. Loesch & Manik Garg & Dorota Matelska & Dimitrios Vitsios & Xiao Jiang & Scott C. Ritchie & Benjamin B. Sun & Heiko Runz & Christopher D. Whelan & Rury R. Holman & Robert J. Mentz & Filipe , 2025. "Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
- Yijun Li & Zhaozhong Zhu & Carlos A. Camargo & Janice A. Espinola & Kohei Hasegawa & Liming Liang, 2025. "Epigenomic and proteomic analyses provide insights into early-life immune regulation and asthma development in infants," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
- Chun Shen & Ruohan Zhang & Jintai Yu & Barbara J. Sahakian & Wei Cheng & Jianfeng Feng, 2025. "Plasma proteomic signatures of social isolation and loneliness associated with morbidity and mortality," Nature Human Behaviour, Nature, vol. 9(3), pages 569-583, March.
- Filippos Anagnostakis & Sarah Ko & Mehrshad Saadatinia & Jingyue Wang & Christos Davatzikos & Junhao Wen, 2025. "Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
- Hongru Li & Jingyi Zhao & Jinglan Dai & Dongfang You & Yang Zhao & David C. Christiani & Feng Chen & Sipeng Shen, 2025. "Multi-ancestry sequencing-based genome-wide association study of C-reactive protein in 513,273 genomes," Nature Communications, Nature, vol. 16(1), pages 1-11, December.
- Abolfazl Doostparast Torshizi & Dongnhu T. Truong & Liping Hou & Bart Smets & Christopher D. Whelan & Shuwei Li, 2024. "Proteogenomic network analysis reveals dysregulated mechanisms and potential mediators in Parkinson’s disease," Nature Communications, Nature, vol. 15(1), pages 1-16, December.