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Valuing EQ-5D health states: A review and analysis, CHERE Working Paper 2007/9


  • Richard Norman

    () (CHERE, University of Technology, Sydney)

  • Paula Cronin

    () (CHERE, University of Technology, Sydney)

  • Rosalie Viney

    () (CHERE, University of Technology, Sydney)

  • Madeleine King

    () (CHERE, University of Technology, Sydney)

  • Deborah Street

    () (University of Technology, Sydney)

  • John Brazier
  • Julie Ratcliffe


Objective: To identify the key methodological issues in the construction of population-level EQ-5D / Time Trade-Off (TTO) preference elicitation studies. Study Design: This study involves three components. The first was to identify existing population-level EQ-5D TTO studies. The second was to illustrate and discuss the key areas of divergence between studies, including the international comparison of tariffs. The third was to portray the relative merits of each of the approaches, and to compare the results of studies across countries. Results: While most papers report use of the protocol developed in the original UK study, we identified three key areas of divergence in the construction and analysis of surveys. These are the number of health states valued in order to determine the algorithm for estimating all health states, the approach to valuing states worse than immediate death, and the choice of algorithm. Finally, the evidence on international comparisons suggests differences between countries, although it is difficult to disentangle differences in cultural attitudes with random error and differences due to methodological divergence. Conclusion: Differences in methods are likely to obscure true differences in values between countries. However, population-specific valuation sets for countries engaging in economic evaluation would better represent societal attitudes.

Suggested Citation

  • Richard Norman & Paula Cronin & Rosalie Viney & Madeleine King & Deborah Street & John Brazier & Julie Ratcliffe, 2007. "Valuing EQ-5D health states: A review and analysis, CHERE Working Paper 2007/9," Working Papers 2007/9, CHERE, University of Technology, Sydney.
  • Handle: RePEc:her:chewps:2007/9

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    File Function: First version, October 2007
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    References listed on IDEAS

    1. Nancy J. Devlin & Paul Hansen & Paul Kind & Alan Williams, 2003. "Logical inconsistencies in survey respondents' health state valuations - a methodological challenge for estimating social tariffs," Health Economics, John Wiley & Sons, Ltd., vol. 12(7), pages 529-544.
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    Cited by:

    1. Richard Norman & Rosalie Viney, 2008. "The effect of discounting on quality of life valuation using the Time Trade-Off, CHERE Working Paper 2008/3," Working Papers 2008/3, CHERE, University of Technology, Sydney.
    2. SeungJin Bae & SooOk Lee & Eun Bae & Sunmee Jang, 2013. "Korean Guidelines for Pharmacoeconomic Evaluation (Second and Updated Version)," PharmacoEconomics, Springer, vol. 31(4), pages 257-267, April.
    3. Nan Luo & Pei Wang & Julian Thumboo & Yee-Wei Lim & Hubertus Vrijhoef, 2014. "Valuation of EQ-5D-3L Health States in Singapore: Modeling of Time Trade-Off Values for 80 Empirically Observed Health States," PharmacoEconomics, Springer, vol. 32(5), pages 495-507, May.
    4. Richard Norman & Paula Cronin & Rosalie Viney, 2013. "A Pilot Discrete Choice Experiment to Explore Preferences for EQ-5D-5L Health States," Applied Health Economics and Health Policy, Springer, vol. 11(3), pages 287-298, June.
    5. Marion Haas & Richard Norman & Jeff Walkley & Leah Brennan, 2009. "Issues in evaluating the costs and cost-effectiveness of Cognitive Behavioural Therapy for overweight/obese adolescents, CHERE Working Paper 2009/1," Working Papers 2009/1, CHERE, University of Technology, Sydney.
    6. Liv Augestad & Kim Rand-Hendriksen & Ivar Kristiansen & Knut Stavem, 2012. "Impact of Transformation of Negative Values and Regression Models on Differences Between the UK and US EQ-5D Time Trade-Off Value Sets," PharmacoEconomics, Springer, vol. 30(12), pages 1203-1214, December.
    7. Richard Norman & Paula Cronin & Rosalie Viney, 2012. "Deriving utility weights for the EQ-5D-5L using a discrete choice experiment. CHERE Working Paper 2012/01," Working Papers 2012/01, CHERE, University of Technology, Sydney.
    8. Klazien Matter-Walstra & Dirk Klingbiel & Thomas Szucs & Bernhard Pestalozzi & Matthias Schwenkglenks, 2014. "Using the EuroQol EQ-5D in Swiss Cancer Patients, Which Value Set Should be Applied?," PharmacoEconomics, Springer, vol. 32(6), pages 591-599, June.
    9. SeungJin Bae & Eun Bae & Sang Lim, 2014. "Sourcing Quality-of-Life Weights Obtained from Previous Studies: Theory and Reality in Korea," The Patient: Patient-Centered Outcomes Research, Springer;Johns Hopkins Bloomberg School of Public Health, vol. 7(2), pages 141-150, June.
    10. Joel Thompson & Amir Abdolahi & Katia Noyes, 2013. "Modelling the Cost Effectiveness of Disease-Modifying Treatments for Multiple Sclerosis," PharmacoEconomics, Springer, vol. 31(6), pages 455-469, June.

    More about this item


    health state valuation; EQ5-D;

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General


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