IDEAS home Printed from
   My bibliography  Save this paper

Economic evaluation of cystic fibrosis screening: A Review of the literature, CHERE Working Paper 2006/6


  • Muralikrishnan Radhakrishnan

    (CHERE, University of Technology, Sydney)

  • Kees van Gool

    () (CHERE, University of Technology, Sydney)

  • Jane Hall

    () (CHERE, University of Technology, Sydney)

  • Martin Delatycki

    (Royal Children's Hopsital, Melbourne)

  • John Massie

    (Royal Children's Hopsital, Melbourne)


Objectives: To critically examine the economic evidence on Cystic Fibrosis (CF) screening and to understand issues relating to the transferability of findings to the Australian context for policy decisions. Methods: A systematic literature search identified 25 economic studies with empirical results on CF published between 1990 and 2005. These articles were then assessed against international benchmarks on conducting and reporting of economic evaluations, focusing on the transferability of the evidence to the local setting. Results: Six studies described only costs, 12 were cost-effectiveness studies, 6 were cost-benefit studies and one had a combined design (cost utility, cost benefit and cost effectiveness). Most of the cost-effectiveness studies compared screening versus ?no-screening? but the screening programs under consideration differed markedly. Four considered neonatal screening, three prenatal screening, three pre-conception and carrier screening, and one considered all types of screening programs. The outcome measures also varied considerably between studies. One study included a quality adjusted life year measure. Cost?benefit measures mostly included economic savings ? evaded lifetime medical costs of avoiding CF child birth. Conclusion: The variability in study design, model inputs and reporting of economic evaluations of CF carrier screening raises issues on the applicability and transferability of such evidence to the Australian context.

Suggested Citation

  • Muralikrishnan Radhakrishnan & Kees van Gool & Jane Hall & Martin Delatycki & John Massie, 2006. "Economic evaluation of cystic fibrosis screening: A Review of the literature, CHERE Working Paper 2006/6," Working Papers 2006/6, CHERE, University of Technology, Sydney.
  • Handle: RePEc:her:chewps:2006/6

    Download full text from publisher

    File URL:
    File Function: First version, September, 2006
    Download Restriction: no

    References listed on IDEAS

    1. Randi Nielsen & Dorte Gyrd-Hansen, 2002. "Prenatal screening for cystic fibrosis: an economic analysis," Health Economics, John Wiley & Sons, Ltd., vol. 11(4), pages 285-299.
    Full references (including those not matched with items on IDEAS)

    More about this item


    Cystic fibrosis; economic evaluation;

    JEL classification:

    • I19 - Health, Education, and Welfare - - Health - - - Other

    NEP fields

    This paper has been announced in the following NEP Reports:


    Access and download statistics


    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:her:chewps:2006/6. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Liz Chinchen). General contact details of provider: .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.