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Industry Life Cycle, Knowledge Generation and Technological Networks

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  • Lionel Nesta

    () (GAEL - Laboratoire d'Economie Appliquée de Grenoble - UPMF - Université Pierre Mendès France - Grenoble 2 - INRA - Institut National de la Recherche Agronomique)

  • Vincent Mangematin

    () (GAEL - Laboratoire d'Economie Appliquée de Grenoble - UPMF - Université Pierre Mendès France - Grenoble 2 - INRA - Institut National de la Recherche Agronomique, MTS - Management Technologique et Strategique - Grenoble École de Management (GEM))

Abstract

This paper examines the links between the rhythm of knowledge generation, the types of actors involved in knowledge generation and the structure of networks of collaborations in the biotech sector. The analysis departs from all biotechnology patent applications covered by Derwent Biotechnology Abstracts (DBA). In 2001, more than 96,000 patents are reported in DBA, covering 40 intellectual property authorities. First, the number of patent applications is continuously increasing, though the number of radical innovations (new technological arrangements) reaches rapidly a steady state. Second, both the number of actors and the number of collaborations follow a bell shape, thus seeming to positively correlate with the rate of technological

Suggested Citation

  • Lionel Nesta & Vincent Mangematin, 2003. "Industry Life Cycle, Knowledge Generation and Technological Networks," Grenoble Ecole de Management (Post-Print) hal-00424163, HAL.
  • Handle: RePEc:hal:gemptp:hal-00424163 Note: View the original document on HAL open archive server: http://hal.grenoble-em.com/hal-00424163
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    References listed on IDEAS

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    1. Vincent Mangematin, 2000. "Competing business models in the french biotech industry," Grenoble Ecole de Management (Post-Print) hal-00422476, HAL.
    2. David J. TEECE, 2008. "Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy," World Scientific Book Chapters,in: The Transfer And Licensing Of Know-How And Intellectual Property Understanding the Multinational Enterprise in the Modern World, chapter 5, pages 67-87 World Scientific Publishing Co. Pte. Ltd..
    3. Klepper, Steven, 1996. "Entry, Exit, Growth, and Innovation over the Product Life Cycle," American Economic Review, American Economic Association, vol. 86(3), pages 562-583, June.
    4. Morten Huse, 2000. "Boards of directors in SMEs: a review and research agenda," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 12(4), pages 271-290, October.
    5. Malerba, Franco & Orsenigo, Luigi, 1996. "Schumpeterian patterns of innovation are technology-specific," Research Policy, Elsevier, vol. 25(3), pages 451-478, May.
    6. Arora, Ashish & Gambardella, Alfonso, 1990. "Complementarity and External Linkages: The Strategies of the Large Firms in Biotechnology," Journal of Industrial Economics, Wiley Blackwell, vol. 38(4), pages 361-379, June.
    7. Garud, Raghu, 1994. "Cooperative and competitive behaviors during the process of creative destruction," Research Policy, Elsevier, vol. 23(4), pages 385-394, July.
    8. Zucker, Lynne G & Darby, Michael R & Brewer, Marilynn B, 1998. "Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises," American Economic Review, American Economic Association, vol. 88(1), pages 290-306, March.
    9. Audretsch, David B & Stephan, Paula E, 1996. "Company-Scientist Locational Links: The Case of Biotechnology," American Economic Review, American Economic Association, vol. 86(3), pages 641-652, June.
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    Cited by:

    1. Malerba, Franco, 2007. "Innovation and the dynamics and evolution of industries: Progress and challenges," International Journal of Industrial Organization, Elsevier, vol. 25(4), pages 675-699, August.
    2. Corolleur, Catherine D. F. & Carrere, M. & Mangematin, V., 2004. "Turning scientific and technological human capital into economic capital: the experience of biotech start-ups in France," Research Policy, Elsevier, vol. 33(4), pages 631-642, May.
    3. Müge Ozman, 2006. "Knowledge Integration and Network Formation," Working Papers of BETA 2006-06, Bureau d'Economie Théorique et Appliquée, UDS, Strasbourg.
    4. Oliver, Amalya L., 2004. "Biotechnology entrepreneurial scientists and their collaborations," Research Policy, Elsevier, vol. 33(4), pages 583-597, May.
    5. Franco Malerba, 2006. "Innovation, Industrial Dynamics and Industry Evolution: Progress and the Research Agendas," Revue de l'OFCE, Presses de Sciences-Po, vol. 97(5), pages 21-46.

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