IDEAS home Printed from https://ideas.repec.org/a/spr/pharme/v34y2016i5d10.1007_s40273-015-0369-5.html
   My bibliography  Save this article

Assessing the Value of New Treatments for Hepatitis C: Are International Decision Makers Getting this Right?

Author

Listed:
  • Beth Woods

    () (University of York)

  • Rita Faria

    () (University of York)

  • Susan Griffin

    (University of York)

Abstract

Abstract Health systems worldwide are facing difficult choices about the use of a series of highly effective but costly new treatments for hepatitis C. In this paper we discuss how the National Institute for Health and Care Excellence in England and Wales, the Common Drug Review in Canada and the Pharmaceutical Benefits Advisory Committee (PBAC) in Australia have approached the appraisal of these drugs. We argue that with the exception of the PBAC, assessments of the new drugs have not adequately accounted for their large financial burden. Given the potential health system impact of reimbursing these drugs, the use of lower cost-effectiveness thresholds should be considered. None of the decision-making processes included a comparison of the full range of treatment pathways. In particular, comparisons of using the new drugs as first- versus second-line drugs were omitted from all appraisals, as were comparisons with delayed treatment strategies whereby treatment is withheld until more severe disease stages. Omission of comparators leads to inaccurate estimates of cost effectiveness and potentially sub-optimal decision making. Lessons learned from these appraisals should be considered in future appraisals, particularly the upcoming assessments of the ‘blockbuster’ PCSK9 inhibitors for hypercholesterolaemia.

Suggested Citation

  • Beth Woods & Rita Faria & Susan Griffin, 2016. "Assessing the Value of New Treatments for Hepatitis C: Are International Decision Makers Getting this Right?," PharmacoEconomics, Springer, vol. 34(5), pages 427-433, May.
  • Handle: RePEc:spr:pharme:v:34:y:2016:i:5:d:10.1007_s40273-015-0369-5
    DOI: 10.1007/s40273-015-0369-5
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s40273-015-0369-5
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Blog mentions

    As found by EconAcademics.org, the blog aggregator for Economics research:
    1. Rita Faria’s journal round-up for 22nd October 2018
      by Rita Faria in The Academic Health Economists' Blog on 2018-10-22 11:00:09

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. repec:spr:aphecp:v:16:y:2018:i:4:d:10.1007_s40258-018-0392-8 is not listed on IDEAS
    2. repec:spr:pharme:v:36:y:2018:i:5:d:10.1007_s40273-017-0604-3 is not listed on IDEAS
    3. repec:spr:pharme:v:36:y:2018:i:9:d:10.1007_s40273-018-0671-0 is not listed on IDEAS

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:pharme:v:34:y:2016:i:5:d:10.1007_s40273-015-0369-5. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Sonal Shukla) or (Rebekah McClure). General contact details of provider: http://www.springer.com .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.