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Inflammatory Bowel Diseases (Crohn´s Disease and Ulcerative Colitis): Cost of Treatment in Serbia and the Implications


  • Marina Kostić

    () (University of Kragujevac)

  • Ljiljan Djakovic

    () (Association of patients with Crohn’s disease and Ulcerative colitis)

  • Raša Šujić

    (Association of patients with Crohn’s disease and Ulcerative colitis)

  • Brian Godman

    () (Karolinska Institute, Karolinska University Hospital Huddinge
    University of Strathclyde
    Liverpool University)

  • Slobodan M. Janković

    () (University of Kragujevac)


Abstract Background Although the costs of treating inflammatory bowel disease (IBD) in developed countries are well established, they remain largely unknown in countries with recent histories of socio-economic transition including Serbia. Objective To estimate the costs of treatment including the resources used by patients with IBD in Serbia from a societal perspective. This includes both Crohn’s disease and ulcerative colitis. Methods This cost-of-illness study was conducted to identify direct, indirect and out-of-pocket costs of treating patients with IBD in Serbia. Patients with IBD (n = 112) completed a semi-structured questionnaire with data concerning their utilisation of heath-care resources and illness-related expenditures. All costs were calculated in Republic of Serbia dinars (RSD) at a 1-year level (2014) and subsequently converted to Euros. Median values and ranges were reported to avoid potential distortions associated with mean costs. Results Median total direct costs and total indirect costs per patient per year in patients with Crohn’s disease were 192,614.32RSD (€1602.97) and 28,014.00RSD (€233.13) and 142,267.15RSD (€1183.97) and 21,436.00RSD (€178.39), respectively, in patients with ulcerative colitis. In both groups, the greatest component of direct costs was hospitalisation. Conclusions Costs of IBD in Serbia are lower than in more developed countries for two reasons. These include the fact that expensive biological therapy is currently under-utilised in Serbia and prices of health services are largely controlled by the State at a low level. The under-utilisation of biologicals may change with the advent of biosimilars at increasingly lower prices.

Suggested Citation

  • Marina Kostić & Ljiljan Djakovic & Raša Šujić & Brian Godman & Slobodan M. Janković, 2017. "Inflammatory Bowel Diseases (Crohn´s Disease and Ulcerative Colitis): Cost of Treatment in Serbia and the Implications," Applied Health Economics and Health Policy, Springer, vol. 15(1), pages 85-93, February.
  • Handle: RePEc:spr:aphecp:v:15:y:2017:i:1:d:10.1007_s40258-016-0272-z
    DOI: 10.1007/s40258-016-0272-z

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    References listed on IDEAS

    1. Renee Stark & Hans-Helmut König & Reiner Leidl, 2006. "Costs of Inflammatory Bowel Disease in Germany," PharmacoEconomics, Springer, vol. 24(8), pages 797-814, August.
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