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Risk of cutaneous squamous cell carcinoma due to occupational exposure to solar ultraviolet radiation: Protocol for a systematic review and meta-analysis

Author

Listed:
  • Marília Silva Paulo
  • Cara Symanzik
  • Balázs Ádam
  • Fabriziomaria Gobba
  • Sanja Kezic
  • Henk F van der Molen
  • Cheryl E Peters
  • Marc Rocholl
  • Thomas Tenkate
  • Swen Malte John
  • Tom Loney
  • Alberto Modenese
  • Marc Wittlich

Abstract

Solar ultraviolet radiation (UVR) is the most significant occupational carcinogenic exposure in terms of the number of workers exposed (i.e., outdoor workers). Consequently, solar UVR-induced skin cancers are among the most common forms of occupational malignancies that are potentially expected globally. This systematic review is registered in PROSPERO (CRD42021295221) and aims to assess the risk of cutaneous squamous cell carcinoma (cSCC) associated to occupational solar UVR exposure. Systematic searches will be performed in three electronic literature databases (PubMed/Medline, EMBASE, and Scopus). Further references will be retrieved by a manual search (e.g., in grey literature databases, internet search engines, and organizational websites). We will include cohort studies and case-control studies. Risk of Bias assessment will be conducted separately for case-control and cohort studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) will be used for the certainty of assessment. In case quantitative pooling is not feasible, a narrative synthesis of results will be performed.

Suggested Citation

  • Marília Silva Paulo & Cara Symanzik & Balázs Ádam & Fabriziomaria Gobba & Sanja Kezic & Henk F van der Molen & Cheryl E Peters & Marc Rocholl & Thomas Tenkate & Swen Malte John & Tom Loney & Alberto M, 2023. "Risk of cutaneous squamous cell carcinoma due to occupational exposure to solar ultraviolet radiation: Protocol for a systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 18(3), pages 1-8, March.
  • Handle: RePEc:plo:pone00:0282664
    DOI: 10.1371/journal.pone.0282664
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    References listed on IDEAS

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    1. Alberto Modenese & Leena Korpinen & Fabriziomaria Gobba, 2018. "Solar Radiation Exposure and Outdoor Work: An Underestimated Occupational Risk," IJERPH, MDPI, vol. 15(10), pages 1-24, September.
    2. Karla Romero Starke & Gabriela Petereit-Haack & Melanie Schubert & Daniel Kämpf & Alexandra Schliebner & Janice Hegewald & Andreas Seidler, 2020. "The Age-Related Risk of Severe Outcomes Due to COVID-19 Infection: A Rapid Review, Meta-Analysis, and Meta-Regression," IJERPH, MDPI, vol. 17(16), pages 1-24, August.
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