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Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference

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  • Anne Kathrine Langerud
  • Tone Rustøen
  • Milada Cvancarova Småstuen
  • Ulf Kongsgaard
  • Audun Stubhaug

Abstract

Background: Experiences during a stay in the intensive care unit (ICU), including pain, delirium, physical deterioration, and the critical illness itself, may all influence survivors’ health-related quality of life (HRQOL). However, few studies have examined the influence of social support, comorbidity, and pain interference on ICU survivors’ HRQOL. Objectives: To investigate possible associations between social support, number of comorbidities, and pain interference on HRQOL in ICU survivors. Methods: ICU survivors responded to a survey 3 months (n = 118) and 1 year (n = 89) after ICU discharge. HRQOL was measured using the Short Form Health Survey-12 (v1), social support using the revised Social Provision Scale, pain interference using the Brief Pain Inventory–Short Form, and comorbidities using the Self-Administered Comorbidity Questionnaire. Results: Physical and mental HRQOL were reduced at both 3 months and 1 year in ICU survivors compared with the general population. This reduction was more pronounced at 3 months for physical HRQOL, while a small reduction in mental HRQOL was not clinically relevant. Social support was statistical significantly positively associated with mental HRQOL at 3 months, while number of comorbidities was statistical significantly associated with a reduction in physical HRQOL at 3 months and 1 year and mental HRQOL at 1 year. Lastly pain interference was significantly associated with a reduction in physical HRQOL at 3 months and 1 year. Conclusions: ICU survivors primarily report reduced physical HRQOL. Social support was positively associated with mental HRQOL, while number of comorbidities, and pain interference were all significantly associated with a reduction in HRQOL. Pain interference was associated with the largest reduction in HRQOL.

Suggested Citation

  • Anne Kathrine Langerud & Tone Rustøen & Milada Cvancarova Småstuen & Ulf Kongsgaard & Audun Stubhaug, 2018. "Health-related quality of life in intensive care survivors: Associations with social support, comorbidity, and pain interference," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-13, June.
  • Handle: RePEc:plo:pone00:0199656
    DOI: 10.1371/journal.pone.0199656
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    1. Sprangers, Mirjam A. G. & Schwartz, Carolyn E., 1999. "Integrating response shift into health-related quality of life research: a theoretical model," Social Science & Medicine, Elsevier, vol. 48(11), pages 1507-1515, June.
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