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Early mortality among children and adults in antiretroviral therapy programs in Southwest Ethiopia, 2003–15

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  • Hailay Abrha Gesesew
  • Paul Ward
  • Kifle Woldemichael
  • Lillian Mwanri

Abstract

Background: Several studies reported that the majority of deaths in HIV-infected people are documented in their early antiretroviral therapy (ART) follow-ups. Early mortality refers to death of people on ART for follow up period of below 24 months due to any cause. The current study assessed predictors of early HIV mortality in Southwest Ethiopia. Methods: We have conducted a retrospective analysis of 5299 patient records dating from June 2003- March 2015. To estimate survival time and compare the time to event among the different groups of patients, we used a Kaplan Meir curve and log-rank test. To identify mortality predictors, we used a cox regression analysis. We used SPSS-20 for all analyses. Results: A total of 326 patients died in the 12 years follow-up period contributing to 6.2% cumulative incidence and 21.7 deaths per 1000 person-year observations incidence rate. Eighty-nine percent of the total deaths were documented in the first two years follow up—an early-term ART follow up. Early HIV mortality rates among adults were 50% less in separated, divorced or widowed patients compared with never married patients, 1.6 times higher in patients with baseline CD4 count

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  • Hailay Abrha Gesesew & Paul Ward & Kifle Woldemichael & Lillian Mwanri, 2018. "Early mortality among children and adults in antiretroviral therapy programs in Southwest Ethiopia, 2003–15," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-17, June.
    • Handle: RePEc:plo:pone00:0198815
    DOI: 10.1371/journal.pone.0198815
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    References listed on IDEAS

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    1. Hailay Abrha Gesesew & Amanuel Tesfay Gebremedhin & Tariku Dejene Demissie & Mirkuzie Woldie Kerie & Morankar Sudhakar & Lillian Mwanri, 2017. "Significant association between perceived HIV related stigma and late presentation for HIV/AIDS care in low and middle-income countries: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 12(3), pages 1-16, March.
    2. Kidane Tadesse & Fisaha Haile & Neway Hiruy, 2014. "Predictors of Mortality among Patients Enrolled on Antiretroviral Therapy in Aksum Hospital, Northern Ethiopia: A Retrospective Cohort Study," PLOS ONE, Public Library of Science, vol. 9(1), pages 1-6, January.
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