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Right atrial volume by cardiovascular magnetic resonance predicts mortality in patients with heart failure with reduced ejection fraction

Author

Listed:
  • Alexander Ivanov
  • Ambreen Mohamed
  • Ahmed Asfour
  • Jean Ho
  • Saadat A Khan
  • Onn Chen
  • Igor Klem
  • Kumudha Ramasubbu
  • Sorin J Brener
  • John F Heitner

Abstract

Background: Right Atrial Volume Index (RAVI) measured by echocardiography is an independent predictor of morbidity in patients with heart failure (HF) with reduced ejection fraction (HFrEF). The aim of this study is to evaluate the predictive value of RAVI assessed by cardiac magnetic resonance (CMR) for all-cause mortality in patients with HFrEF and to assess its additive contribution to the validated Meta-Analysis Global Group in Chronic heart failure (MAGGIC) score. Methods and results: We identified 243 patients (mean age 60 ± 15; 33% women) with left ventricular ejection fraction (LVEF) ≤ 35% measured by CMR. Right atrial volume was calculated based on area in two- and four -chamber views using validated equation, followed by indexing to body surface area. MAGGIC score was calculated using online calculator. During mean period of 2.4 years 33 patients (14%) died. The mean RAVI was 53 ± 26 ml/m2; significantly larger in patients with than without an event (78.7±29 ml/m2 vs. 48±22 ml/m2, p

Suggested Citation

  • Alexander Ivanov & Ambreen Mohamed & Ahmed Asfour & Jean Ho & Saadat A Khan & Onn Chen & Igor Klem & Kumudha Ramasubbu & Sorin J Brener & John F Heitner, 2017. "Right atrial volume by cardiovascular magnetic resonance predicts mortality in patients with heart failure with reduced ejection fraction," PLOS ONE, Public Library of Science, vol. 12(4), pages 1-13, April.
  • Handle: RePEc:plo:pone00:0173245
    DOI: 10.1371/journal.pone.0173245
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    References listed on IDEAS

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    1. Patrick J. Heagerty & Thomas Lumley & Margaret S. Pepe, 2000. "Time-Dependent ROC Curves for Censored Survival Data and a Diagnostic Marker," Biometrics, The International Biometric Society, vol. 56(2), pages 337-344, June.
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    1. Marina Strocchi & Christoph M Augustin & Matthias A F Gsell & Elias Karabelas & Aurel Neic & Karli Gillette & Orod Razeghi & Anton J Prassl & Edward J Vigmond & Jonathan M Behar & Justin Gould & Balde, 2020. "A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-26, June.

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