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Global Economic Burden of Norovirus Gastroenteritis

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  • Sarah M Bartsch
  • Benjamin A Lopman
  • Sachiko Ozawa
  • Aron J Hall
  • Bruce Y Lee

Abstract

Background: Despite accounting for approximately one fifth of all acute gastroenteritis illnesses, norovirus has received comparatively less attention than other infectious pathogens. With several candidate vaccines under development, characterizing the global economic burden of norovirus could help funders, policy makers, public health officials, and product developers determine how much attention and resources to allocate to advancing these technologies to prevent and control norovirus. Methods: We developed a computational simulation model to estimate the economic burden of norovirus in every country/area (233 total) stratified by WHO region and globally, from the health system and societal perspectives. We considered direct costs of illness (e.g., clinic visits and hospitalization) and productivity losses. Results: Globally, norovirus resulted in a total of $4.2 billion (95% UI: $3.2–5.7 billion) in direct health system costs and $60.3 billion (95% UI: $44.4–83.4 billion) in societal costs per year. Disease amongst children

Suggested Citation

  • Sarah M Bartsch & Benjamin A Lopman & Sachiko Ozawa & Aron J Hall & Bruce Y Lee, 2016. "Global Economic Burden of Norovirus Gastroenteritis," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-16, April.
    • Handle: RePEc:plo:pone00:0151219
    DOI: 10.1371/journal.pone.0151219
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    References listed on IDEAS

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    1. Tharani Loganathan & Way-Seah Lee & Kok-Foo Lee & Mark Jit & Chiu-Wan Ng, 2015. "Household Catastrophic Healthcare Expenditure and Impoverishment Due to Rotavirus Gastroenteritis Requiring Hospitalization in Malaysia," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-14, May.
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    1. Ascioti, Fortunato A. & Mangano, Maria Cristina & Marcianò, Claudio & Sarà , Gianluca, 2022. "The sanitation service of seagrasses – Dependencies and implications for the estimation of avoided costs," Ecosystem Services, Elsevier, vol. 54(C).
    2. Lane, David & Husemann, Elke & Holland, Darren & Khaled, Abdul, 2019. "Understanding foodborne transmission mechanisms for Norovirus: A study for the UK's Food Standards Agency," European Journal of Operational Research, Elsevier, vol. 275(2), pages 721-736.
    3. Shenglan Xiao & Julian W. Tang & Yuguo Li, 2017. "Airborne or Fomite Transmission for Norovirus? A Case Study Revisited," IJERPH, MDPI, vol. 14(12), pages 1-10, December.
    4. Shokhrukh-Mirzo Jalilov & Mohamed Kefi & Pankaj Kumar & Yoshifumi Masago & Binaya Kumar Mishra, 2018. "Sustainable Urban Water Management: Application for Integrated Assessment in Southeast Asia," Sustainability, MDPI, vol. 10(1), pages 1-22, January.
    5. Wilhelm Salmen & Liya Hu & Marina Bok & Natthawan Chaimongkol & Khalil Ettayebi & Stanislav V. Sosnovtsev & Kaundal Soni & B. Vijayalakshmi Ayyar & Sreejesh Shanker & Frederick H. Neill & Banumathi Sa, 2023. "A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    6. Gabriela Alvarado & Wilhelm Salmen & Khalil Ettayebi & Liya Hu & Banumathi Sankaran & Mary K. Estes & B. V. Venkataram Prasad & James E. Crowe, 2021. "Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses," Nature Communications, Nature, vol. 12(1), pages 1-13, December.

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