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Primacy of vision shapes behavioral strategies and neural substrates of spatial navigation in marmoset hippocampus

Author

Listed:
  • Diego B. Piza

    (Western University
    Western University)

  • Benjamin W. Corrigan

    (Western University
    Western University
    York University)

  • Roberto A. Gulli

    (Columbia University)

  • Sonia Carmo

    (McGill University)

  • A. Claudio Cuello

    (McGill University)

  • Lyle Muller

    (Western University
    Western University)

  • Julio Martinez-Trujillo

    (Western University
    Western University
    Western University
    Western University)

Abstract

The role of the hippocampus in spatial navigation has been primarily studied in nocturnal mammals, such as rats, that lack many adaptations for daylight vision. Here we demonstrate that during 3D navigation, the common marmoset, a new world primate adapted to daylight, predominantly uses rapid head-gaze shifts for visual exploration while remaining stationary. During active locomotion marmosets stabilize the head, in contrast to rats that use low-velocity head movements to scan the environment as they locomote. Pyramidal neurons in the marmoset hippocampus CA3/CA1 regions predominantly show mixed selectivity for 3D spatial view, head direction, and place. Exclusive place selectivity is scarce. Inhibitory interneurons are predominantly mixed selective for angular head velocity and translation speed. Finally, we found theta phase resetting of local field potential oscillations triggered by head-gaze shifts. Our findings indicate that marmosets adapted to their daylight ecological niche by modifying exploration/navigation strategies and their corresponding hippocampal specializations.

Suggested Citation

  • Diego B. Piza & Benjamin W. Corrigan & Roberto A. Gulli & Sonia Carmo & A. Claudio Cuello & Lyle Muller & Julio Martinez-Trujillo, 2024. "Primacy of vision shapes behavioral strategies and neural substrates of spatial navigation in marmoset hippocampus," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-48374-2
    DOI: 10.1038/s41467-024-48374-2
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    1. Marie E. Vericel & Pierre Baraduc & Jean-René Duhamel & Sylvia Wirth, 2024. "Organizing space through saccades and fixations between primate posterior parietal cortex and hippocampus," Nature Communications, Nature, vol. 15(1), pages 1-20, December.

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