IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v13y2022i1d10.1038_s41467-022-34197-6.html
   My bibliography  Save this article

Quantitative phase contrast imaging with a nonlocal angle-selective metasurface

Author

Listed:
  • Anqi Ji

    (Stanford University)

  • Jung-Hwan Song

    (Stanford University)

  • Qitong Li

    (Stanford University)

  • Fenghao Xu

    (Stanford University)

  • Ching-Ting Tsai

    (Stanford University)

  • Richard C. Tiberio

    (Stanford University)

  • Bianxiao Cui

    (Stanford University)

  • Philippe Lalanne

    (University of Bordeaux)

  • Pieter G. Kik

    (University of Central Florida)

  • David A. B. Miller

    (Stanford University)

  • Mark L. Brongersma

    (Stanford University)

Abstract

Phase contrast microscopy has played a central role in the development of modern biology, geology, and nanotechnology. It can visualize the structure of translucent objects that remains hidden in regular optical microscopes. The optical layout of a phase contrast microscope is based on a 4 f image processing setup and has essentially remained unchanged since its invention by Zernike in the early 1930s. Here, we propose a conceptually new approach to phase contrast imaging that harnesses the non-local optical response of a guided-mode-resonator metasurface. We highlight its benefits and demonstrate the imaging of various phase objects, including biological cells, polymeric nanostructures, and transparent metasurfaces. Our results showcase that the addition of this non-local metasurface to a conventional microscope enables quantitative phase contrast imaging with a 0.02π phase accuracy. At a high level, this work adds to the growing body of research aimed at the use of metasurfaces for analog optical computing.

Suggested Citation

  • Anqi Ji & Jung-Hwan Song & Qitong Li & Fenghao Xu & Ching-Ting Tsai & Richard C. Tiberio & Bianxiao Cui & Philippe Lalanne & Pieter G. Kik & David A. B. Miller & Mark L. Brongersma, 2022. "Quantitative phase contrast imaging with a nonlocal angle-selective metasurface," Nature Communications, Nature, vol. 13(1), pages 1-7, December.
  • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-34197-6
    DOI: 10.1038/s41467-022-34197-6
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-022-34197-6
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/s41467-022-34197-6?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Gordon Wetzstein & Aydogan Ozcan & Sylvain Gigan & Shanhui Fan & Dirk Englund & Marin Soljačić & Cornelia Denz & David A. B. Miller & Demetri Psaltis, 2020. "Inference in artificial intelligence with deep optics and photonics," Nature, Nature, vol. 588(7836), pages 39-47, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. H. H. Zhu & J. Zou & H. Zhang & Y. Z. Shi & S. B. Luo & N. Wang & H. Cai & L. X. Wan & B. Wang & X. D. Jiang & J. Thompson & X. S. Luo & X. H. Zhou & L. M. Xiao & W. Huang & L. Patrick & M. Gu & L. C., 2022. "Space-efficient optical computing with an integrated chip diffractive neural network," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    2. Yaoyao Shi & Wei Sheng & Yangyang Fu & Youwen Liu, 2023. "Overlapping speckle correlation algorithm for high-resolution imaging and tracking of objects in unknown scattering media," Nature Communications, Nature, vol. 14(1), pages 1-8, December.
    3. Takuya Nakata & Sinan Chen & Masahide Nakamura, 2022. "Uni-Messe: Unified Rule-Based Message Delivery Service for Efficient Context-Aware Service Integration," Energies, MDPI, vol. 15(5), pages 1-18, February.
    4. Elena Goi & Steffen Schoenhardt & Min Gu, 2022. "Direct retrieval of Zernike-based pupil functions using integrated diffractive deep neural networks," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    5. Yuriy Leonidovich Zhukovskiy & Daria Evgenievna Batueva & Alexandra Dmitrievna Buldysko & Bernard Gil & Valeriia Vladimirovna Starshaia, 2021. "Fossil Energy in the Framework of Sustainable Development: Analysis of Prospects and Development of Forecast Scenarios," Energies, MDPI, vol. 14(17), pages 1-28, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-34197-6. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.