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Bottom-up assembly of viral replication cycles

Author

Listed:
  • Oskar Staufer

    (University of Bristol
    University of Oxford
    Max Planck School Matter to Life)

  • Gösta Gantner

    (Max Planck School Matter to Life
    Heidelberg University)

  • Ilia Platzman

    (University of Bristol
    Max Planck Institute for Medical Research
    University of Heidelberg)

  • Klaus Tanner

    (Max Planck School Matter to Life
    Heidelberg University)

  • Imre Berger

    (University of Bristol
    University of Bristol
    University of Bristol)

  • Joachim P. Spatz

    (University of Bristol
    Max Planck School Matter to Life
    Max Planck Institute for Medical Research
    University of Heidelberg)

Abstract

Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.

Suggested Citation

  • Oskar Staufer & Gösta Gantner & Ilia Platzman & Klaus Tanner & Imre Berger & Joachim P. Spatz, 2022. "Bottom-up assembly of viral replication cycles," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33661-7
    DOI: 10.1038/s41467-022-33661-7
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    References listed on IDEAS

    as
    1. Sara Reardon, 2014. "US suspends risky disease research," Nature, Nature, vol. 514(7523), pages 411-412, October.
    2. Oskar Staufer & Kapil Gupta & Jochen Estebano Hernandez Bücher & Fabian Kohler & Christian Sigl & Gunjita Singh & Kate Vasileiou & Ana Yagüe Relimpio & Meline Macher & Sebastian Fabritz & Hendrik Diet, 2022. "Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    3. Tina Wiegand & Marta Fratini & Felix Frey & Klaus Yserentant & Yang Liu & Eva Weber & Kornelia Galior & Julia Ohmes & Felix Braun & Dirk-Peter Herten & Steeve Boulant & Ulrich S. Schwarz & Khalid Sala, 2020. "Forces during cellular uptake of viruses and nanoparticles at the ventral side," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
    4. Steffen Foss Hansen & Martin Krayer von Krauss & Joel A. Tickner, 2008. "The precautionary principle and risk-risk tradeoffs," Journal of Risk Research, Taylor & Francis Journals, vol. 11(4), pages 423-464, June.
    5. Tran Thao & Fabien Labroussaa & Nadine Ebert & Philip V’kovski & Hanspeter Stalder & Jasmine Portmann & Jenna Kelly & Silvio Steiner & Melle Holwerda & Annika Kratzel & Mitra Gultom & Kimberly Schmied, 2020. "Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform," Nature, Nature, vol. 582(7813), pages 561-565, June.
    6. Carolina Villarroya-Beltri & Cristina Gutiérrez-Vázquez & Fátima Sánchez-Cabo & Daniel Pérez-Hernández & Jesús Vázquez & Noa Martin-Cofreces & Dannys Jorge Martinez-Herrera & Alberto Pascual-Montano &, 2013. "Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs," Nature Communications, Nature, vol. 4(1), pages 1-10, December.
    7. Thomas A. Dixon & Paul S. Freemont & Richard A. Johnson & Isak S. Pretorius, 2022. "A global forum on synthetic biology: the need for international engagement," Nature Communications, Nature, vol. 13(1), pages 1-5, December.
    8. Omer Adir & Mia R. Albalak & Ravit Abel & Lucien E. Weiss & Gal Chen & Amit Gruber & Oskar Staufer & Yaniv Kurman & Ido Kaminer & Jeny Shklover & Janna Shainsky-Roitman & Ilia Platzman & Lior Gepstein, 2022. "Synthetic cells with self-activating optogenetic proteins communicate with natural cells," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    9. Masaki Imai & Tokiko Watanabe & Masato Hatta & Subash C. Das & Makoto Ozawa & Kyoko Shinya & Gongxun Zhong & Anthony Hanson & Hiroaki Katsura & Shinji Watanabe & Chengjun Li & Eiryo Kawakami & Shinya , 2012. "Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets," Nature, Nature, vol. 486(7403), pages 420-428, June.
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