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Synthesis of 6H-thiochromeno [3, 4-b] Quinoxaline Derivatives and their Antifungal Activities

Author

Listed:
  • Peng Wei
  • Jingjing Liu
  • Junjie Ma
  • Gengliang Yang

Abstract

Objective- To design to synthesize 6H-thiochromeno [3, 4-b] quinoxaline derivatives and evaluate their antifungal activities. Methods- The target compounds were prepared from substituted thiophenol by several steps, and separated by column chromatography. Results- Four new unreported compounds were obtained. All compounds were confirmed by 1 H NMR and MS spectral analysis. Preliminary pharmacological test showed that two compounds both possessed potential antifungal activities.Conclusion- The synthesized 6H-thiochromeno [3, 4-b] quinoxaline derivatives had certain antifungal activities in some tested fungal strains in vitro.

Suggested Citation

  • Peng Wei & Jingjing Liu & Junjie Ma & Gengliang Yang, 2010. "Synthesis of 6H-thiochromeno [3, 4-b] Quinoxaline Derivatives and their Antifungal Activities," Modern Applied Science, Canadian Center of Science and Education, vol. 4(12), pages 136-136, December.
    • Handle: RePEc:ibn:masjnl:v:4:y:2010:i:12:p:136
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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