IDEAS home Printed from https://ideas.repec.org/a/ibn/ijpsjl/v4y2012i3p73.html
   My bibliography  Save this article

Effect of Early Stimulation on Some Immune Parameters in a Model of Prenatally Stressed Rats

Author

Listed:
  • Ana Liaudat
  • Nancy Rodríguez
  • Adriana Vivas
  • Héctor Gauna
  • Nora Mayer

Abstract

The aim of this research was to investigate the effects of prenatal stress and handling on immune system celldistribution and lymphocyte T proliferation in adult Albino Wistar male rats. Prenatal stressed (PS) offspring byimmobilization (IMO) were handled during the first week of life. Animals of both treatments were acute IMOstressed. Blood was extracted from 0 to 330 min, and counting of white blood cells, leucocyte subpopulationsand levels of corticosterone (COR) were made. Lymphocyte T spleen proliferation was determined. COR,leucocyte, lymphocyte and neutrophil profiles and lymphocyte T proliferation were significant different betweenprenatal stress and non-handling group and prenatal control and non-handling group, however these responseswere attenuated when animals were handled. In conclusion, early handling revert the effects of PS withre-exposure to the same postnatal stressor on the activity of hypothalamo-pituitary-adrenal axis, the dynamic ofleucocyte distribution and the mitogenic response of T lymphocytes.

Suggested Citation

  • Ana Liaudat & Nancy Rodríguez & Adriana Vivas & Héctor Gauna & Nora Mayer, 2012. "Effect of Early Stimulation on Some Immune Parameters in a Model of Prenatally Stressed Rats," International Journal of Psychological Studies, Canadian Center of Science and Education, vol. 4(3), pages 1-73, September.
    • Handle: RePEc:ibn:ijpsjl:v:4:y:2012:i:3:p:73
    as

    Download full text from publisher

    File URL: https://ccsenet.org/journal/index.php/ijps/article/download/15683/13149
    Download Restriction: no
    File URL: https://ccsenet.org/journal/index.php/ijps/article/view/15683
    Download Restriction: no
    ---><---

    More about this item

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:ibn:ijpsjl:v:4:y:2012:i:3:p:73. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Canadian Center of Science and Education (email available below). General contact details of provider: https://edirc.repec.org/data/cepflch.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.