Labile Iron Controllng Therapy To Prevent Cancers and Alzheimer’s Disease

It has been pointed out that so-called plasma labile iron (or NTBI = non-transferrin-bound iron) is the essential cause of many cancers and Alzheimer’s disease, but its actual properties have not been clarified. Nishida have concluded that the structure of highly toxic plasma labile iron is an oxo-bridged diiron species through the experimental results using many artificial iron chelating agents. Based on this result, he synthesized non-toxic chelating agents (SP9 and SP10) that prevent the formation of the oxo-bridged di-iron species, and found that these chelates effectively suppress the proliferation of various types of cancers, proving the correctness of his conclusion. He also obtained many related results which support that SP9 and SP10 can be applied to prevent Alzheimer’s disease. Furthermore, Nishida have demonstrated that some zinc ions can remove these dangerous oxo-bridged diiron species through the formation of iron deposition. Nishida have shown that his universal healthcare, so-called “Labile Iron Controllng Therapy” (LICT), which prevents cancers and Alzheimer’s disease through suppressing the formation of dangerous oxo-bridged di-iron species in the human body, can be achieved through daily diet that contain suitable zinc ions and natural lignin derivatives.