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Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Function in Patients With Coronary Artery Disease

Author

Listed:
  • Nahid Salehi
  • Mohammadreza Saidi
  • Alireza Rai
  • Farid Najafi
  • Seedmokhtar Javeedannejad
  • Mehran Babanejad
  • Hooman Tadbiri

Abstract

BACKGROUND- There is considerable disagreement over the effects of percutaneous coronary intervention (PCI) on left ventricular diastolic function that has necessitated the investigation of diastolic indices. The present study was conducted to evaluate left ventricular diastolic function and its indices, three months after performing the PCI procedure in patients with coronary artery disease (CAD). METHODS- In a quasi-experimental clinical trial study (before and after), 51 patients with CAD scheduled for elective PCI were investigated provided that their Ejection Fraction (EF) was > 30%. Before and three months after PCI, echocardiography was carried out to evaluate left ventricular diastolic indices including the E/Ea as the most important criteria for diagnosis of diastolic heart failure (DHF). RESULTS- Based on the E/Ea indices and after PCI, the number of patients with DHF decreased significantly- 40 patients (78.4%) before PCI versus 28 patients (54.9%) after PCI (p<0.05). The Mean and Standard error of deceleration time (DT), isovolumic relaxation time (IVRT), early diastolic mitral annulus velocity; Ea (E'), E/Ea and left ventricular ejection function (LVEF) indices underwent significant changes. In addition, MVA dur/PVA dur, PVs/PVd, and E/Ea indices had changed significantly after PCI in both genders. However, no significant difference was reported for the other indices. CONCLUSION- The E/Ea ratio as an important criterion for diagnosis of DHF was improved after PCI. Improvement of several other diastolic indices was observed after the PCI procedure. It can be concluded that PCI can be an effective treatment modality in patients with left ventricular diastolic indices.

Suggested Citation

  • Nahid Salehi & Mohammadreza Saidi & Alireza Rai & Farid Najafi & Seedmokhtar Javeedannejad & Mehran Babanejad & Hooman Tadbiri, 2016. "Effect of Percutaneous Coronary Intervention on Left Ventricular Diastolic Function in Patients With Coronary Artery Disease," Global Journal of Health Science, Canadian Center of Science and Education, vol. 8(1), pages 270-270, January.
    • Handle: RePEc:ibn:gjhsjl:v:8:y:2016:i:1:p:270
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    References listed on IDEAS

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    1. Fereidoun Azizi & Maziar Rahmani & Habib Emami & P. Mirmiran & R. Hajipour & M. Madjid & J. Ghanbili & A. Ghanbarian & J. Mehrabi & N. Saadat & P. Salehi & N. Mortazavi & P. Heydarian & N. Sarbazi & S, 2002. "Cardiovascular risk factors in an Iranian urban population: Tehran Lipid and Glucose Study (Phase 1)," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 47(6), pages 408-426, December.
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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