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The Impact of COVID-19 on Pediatric Cardiac Arrest Outcomes: A Systematic Review and Meta-Analysis

Author

Listed:
  • Alla Navolokina

    (European School of Medicine, International European University, 03187 Kyiv, Ukraine)

  • Jacek Smereka

    (Department of Emergency Medical Service, Wroclaw Medical University, 51-616 Wroclaw, Poland
    Research Unit, Polish Society of Disaster Medicine, 05-806 Warsaw, Poland)

  • Bernd W. Böttiger

    (Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, 50937 Cologne, Germany)

  • Michal Pruc

    (Research Unit, Polish Society of Disaster Medicine, 05-806 Warsaw, Poland)

  • Raúl Juárez-Vela

    (GRUPAC, Department in Nursing, University of La Rioja, 26006 Logroño, Spain)

  • Mansur Rahnama-Hezavah

    (Chair and Department of Oral Surgery, Medical University of Lublin, 20-093 Lublin, Poland)

  • Zubaid Rafique

    (Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX 77030, USA)

  • Frank W. Peacock

    (Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX 77030, USA)

  • Kamil Safiejko

    (Research Unit, Maria Sklodowska-Curie Bialystok Oncology Center, 15-294 Bialystok, Poland)

  • Lukasz Szarpak

    (Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX 77030, USA)

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic, required the donning of personal protective equipment during clinical contact, and continues to be a significant worldwide public health concern. Pediatric cardiac arrest is a rare but critical condition with a high mortality rate, the outcomes of which may be negatively affected by donning personal protective equipment. The aim of this study is to perform a systematic review and meta-analysis of the impact of the COVID-19 pandemic on pediatric cardiac arrest outcomes. We conducted a systematic review with meta-analysis in the following databases: PubMed, EMBASE, Scopus, Web of Science, and Cochrane Library from their inception to 1 October 2022. We included studies published in English on pediatric patients with cardiac arrest, dichotomized by the pre- and during-COVID-19 periods and then stratified by COVID-19 positive or negative status, to evaluate clinical outcomes associated with cardiac arrest. Six studies were included in the meta-analysis. In witnessed out-of-hospital cardiac arrest patients, there were no differences between the pandemic and pre-pandemic periods for witnessed cardiac arrest (28.5% vs. 28.7%; odds ratio (OR) = 0.99; 95% confidence interval (CI): 0.87 to 1.14; p = 0.93), administration of bystander cardiopulmonary resuscitation (61.5 vs. 63.6%; OR = 1.11; 95%CI: 0.98 to 1.26; p = 0.11), bystander automated external defibrillator use (both 2.8%; OR = 1.00; 95%CI: 0.69 to 1.45; p = 0.99), return of spontaneous circulation(8.4 vs. 8.9%; OR = 0.93; 95%CI: 0.47 to 1.88; p = 0.85), survival to hospital admission (9.0 vs. 10.2%, OR = 0.81; 95%CI: 0.45 to 1.44; p = 0.47), or survival to hospital discharge (13.4 vs. 12.4%; OR = 0.62; 95%CI: 0.22 to 1.72; p = 0.35). COVID-19 did not change pediatric cardiac arrest bystander interventions or outcomes.

Suggested Citation

  • Alla Navolokina & Jacek Smereka & Bernd W. Böttiger & Michal Pruc & Raúl Juárez-Vela & Mansur Rahnama-Hezavah & Zubaid Rafique & Frank W. Peacock & Kamil Safiejko & Lukasz Szarpak, 2023. "The Impact of COVID-19 on Pediatric Cardiac Arrest Outcomes: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(2), pages 1-9, January.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1104-:d:1028824
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    References listed on IDEAS

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    2. Peng Zhou & Xing-Lou Yang & Xian-Guang Wang & Ben Hu & Lei Zhang & Wei Zhang & Hao-Rui Si & Yan Zhu & Bei Li & Chao-Lin Huang & Hui-Dong Chen & Jing Chen & Yun Luo & Hua Guo & Ren-Di Jiang & Mei-Qin L, 2020. "A pneumonia outbreak associated with a new coronavirus of probable bat origin," Nature, Nature, vol. 579(7798), pages 270-273, March.
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