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Approaches to Peripheral Artery Disease in Diabetes: Are There Any Differences?

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  • Alexandru Achim

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania
    ”Niculae Stancioiu” Heart Institute, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania
    Klinik für Kardiologie, Medizinische Universitätsklinik, Kantonsspital Baselland, 4410 Liestal, Switzerland
    Internal Medicine Department, Division of Invasive Cardiology, University of Szeged, 6720 Szeged, Hungary)

  • Agata Stanek

    (Department of Internal Medicine, Angiology and Physical Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Batorego 15 St., 41-902 Bytom, Poland)

  • Călin Homorodean

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

  • Mihail Spinu

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

  • Horea Laurenţiu Onea

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

  • Leontin Lazăr

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

  • Mădălin Marc

    (”Niculae Stancioiu” Heart Institute, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

  • Zoltán Ruzsa

    (Internal Medicine Department, Division of Invasive Cardiology, University of Szeged, 6720 Szeged, Hungary)

  • Dan Mircea Olinic

    (Medical 1 Clinic, Department of Interventional Cardiology, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400000 Cluj-Napoca, Romania)

Abstract

Peripheral artery disease (PAD) increases the risk of diabetes, while diabetes increases the risk of PAD, and certain symptoms in each disease increase the risk of contracting the other. This review aims to shed light on this harmful interplay between the two disorders, with an emphasis on the phenotype of a patient with both diabetes and PAD, and whether treatment should be individualized in this high-risk population. In addition, current guideline recommendations for the treatment of PAD were analyzed, in an attempt to establish the differences and evidence gaps across a population suffering from these two interconnected disorders.

Suggested Citation

  • Alexandru Achim & Agata Stanek & Călin Homorodean & Mihail Spinu & Horea Laurenţiu Onea & Leontin Lazăr & Mădălin Marc & Zoltán Ruzsa & Dan Mircea Olinic, 2022. "Approaches to Peripheral Artery Disease in Diabetes: Are There Any Differences?," IJERPH, MDPI, vol. 19(16), pages 1-11, August.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:16:p:9801-:d:883855
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    References listed on IDEAS

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    1. Grzegorz K. Jakubiak & Natalia Pawlas & Grzegorz Cieślar & Agata Stanek, 2021. "Pathogenesis and Clinical Significance of In-Stent Restenosis in Patients with Diabetes," IJERPH, MDPI, vol. 18(22), pages 1-23, November.
    2. Reiner A. Wimmer & Alexandra Leopoldi & Martin Aichinger & Nikolaus Wick & Brigitte Hantusch & Maria Novatchkova & Jasmin Taubenschmid & Monika Hämmerle & Christopher Esk & Joshua A. Bagley & Dominik , 2019. "Human blood vessel organoids as a model of diabetic vasculopathy," Nature, Nature, vol. 565(7740), pages 505-510, January.
    3. Grzegorz K. Jakubiak & Natalia Pawlas & Grzegorz Cieślar & Agata Stanek, 2020. "Chronic Lower Extremity Ischemia and Its Association with the Frailty Syndrome in Patients with Diabetes," IJERPH, MDPI, vol. 17(24), pages 1-17, December.
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    1. Lilla Horváth & Imre Boncz & Zsuzsanna Kívés & Gergely Fehér & Noémi Németh & Fanni Luca Kajos & Katalin Biró & Krisztina Fendrik & Katalin Koltai & Gábor Késmárky & Dóra Endrei, 2023. "Disease-Specific Quality of Life among Patients with Peripheral Artery Disease in Hungary," IJERPH, MDPI, vol. 20(4), pages 1-14, February.

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