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Prevalence and Subtype Distribution of Blastocystis Infection in Patients with Diabetes Mellitus in Thailand

Author

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  • Noppon Popruk

    (Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand)

  • Satakamol Prasongwattana

    (Department of Nursing, Bang Pa-in Hospital, Bang Pa-in District, Phra Nakhon Si Ayutthaya 13160, Thailand)

  • Aongart Mahittikorn

    (Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand)

  • Attakorn Palasuwan

    (Oxidation in Red Cell Disorders Research Unit, Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand)

  • Supaluk Popruk

    (Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand)

  • Duangdao Palasuwan

    (Oxidation in Red Cell Disorders Research Unit, Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand)

Abstract

Diabetes mellitus (DM) is a major global public health problem with an increasing prevalence. DM increases the risk of infections caused by bacteria, fungi, viruses, and parasites. We examined the prevalence, subtypes, and risk factors of Blastocystis infection in patients with and without DM in central Thailand. Stool samples and questionnaires were obtained from 130 people in the DM group and 100 people in the non-DM group. Blastocystis infection was identified via a nested polymerase chain reaction and subtyped via sequencing of the partial small-subunit ribosomal RNA (SSU rRNA) gene. Analysis of potential risk factors was conducted via binary logistic regression. The overall prevalence of Blastocystis infection was 10.8%, including rates of 9% and 12.3% in the non-DM and DM groups, respectively. The most prevalent subtype was ST3, followed by ST1, and ST4. Factors that potentially increased the risk of Blastocystis infection include patients being >65 years old, the presence of DM, a DM duration of ≥10 years, a low level of education, and animal ownership. In conclusion, this is the first study of Blastocystis infection in DM, and a high prevalence was found among this population. Therefore, health education promoting sanitation and hygiene is necessary to reduce and prevent infection in the community.

Suggested Citation

  • Noppon Popruk & Satakamol Prasongwattana & Aongart Mahittikorn & Attakorn Palasuwan & Supaluk Popruk & Duangdao Palasuwan, 2020. "Prevalence and Subtype Distribution of Blastocystis Infection in Patients with Diabetes Mellitus in Thailand," IJERPH, MDPI, vol. 17(23), pages 1-12, November.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:23:p:8877-:d:453266
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    References listed on IDEAS

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    1. Junjie Qin & Yingrui Li & Zhiming Cai & Shenghui Li & Jianfeng Zhu & Fan Zhang & Suisha Liang & Wenwei Zhang & Yuanlin Guan & Dongqian Shen & Yangqing Peng & Dongya Zhang & Zhuye Jie & Wenxian Wu & Yo, 2012. "A metagenome-wide association study of gut microbiota in type 2 diabetes," Nature, Nature, vol. 490(7418), pages 55-60, October.
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    1. Amanee Abu & Chantira Sutthikornchai & Aongart Mahittikorn & Khuanchai Koompapong & Rachatawan Chiabchalard & Dumrongkiet Arthan & Ngamphol Soonthornworasiri & Supaluk Popruk, 2022. "Prevalence and Subtype Distribution of Blastocystis Isolated from School-Aged Children in the Thai-Myanmar Border, Ratchaburi Province, Thailand," IJERPH, MDPI, vol. 20(1), pages 1-9, December.

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