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Progress and Understandings in the Pharmacological Repositioning Scenario

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  • Lara Bianca Soares Brandão
  • Dicla Aline Semedo da Veiga
  • Hélida Maravilha Dantas e Sousa Almeida
  • Igor de Sousa Oliveira
  • Sávio Benvido Ferreira

Abstract

In order to present an overview of pharmacological repositioning in terms of clinical applicability, a narrative review was applied, based on the PCC strategy. The search was carried out in February 2022, highlighting the concepts on the subject, not requiring the opinion of a committee for its development. Numerous drugs were randomly repositioned. It is noteworthy that during clinical trials, unexpected side effects made its reuse possible. The antiplatelet effect of aspirin is already elucidated, however, research reveals potential in oncology. Therefore, there is a need to explore the biochemistry and the interaction with organic and pathological targets, visualizing the applicability of known drugs in solving urgent problems.

Suggested Citation

  • Lara Bianca Soares Brandão & Dicla Aline Semedo da Veiga & Hélida Maravilha Dantas e Sousa Almeida & Igor de Sousa Oliveira & Sávio Benvido Ferreira, 2023. "Progress and Understandings in the Pharmacological Repositioning Scenario," European Journal of Medical and Health Sciences, European Open Science, vol. 5(1), pages 28-31, January.
    • Handle: RePEc:epw:ejmed0:v:5:y:2023:i:1:id:41660
    DOI: 10.24018/ejmed.2023.5.1.1660
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    References listed on IDEAS

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    1. Nicola Nosengo, 2016. "Can you teach old drugs new tricks?," Nature, Nature, vol. 534(7607), pages 314-316, June.
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