A guide to efficient keyword, sequence and classification search strategies for biopharmaceutical drug-centric patent landscape searches - A human recombinant insulin patent landscape case study

Searching biopharmaceutical drug-related patent information is generally considered to be challenging. In particular, setting up efficient search strategies for comprehensive retrieval of high amounts of patent documents related to processes and methods of use, that achieve a reasonable level of precision, but still remain within a particular search scope. While it is generally accepted that patent information cannot be searched using standardized approaches, it is desirable to have a basic rule set for successful biopharmaceutical drug-related patent information retrieval, particularly facing a steady flow of patent expirations for prominent biologic drugs. The present human recombinant insulin case study shows an assessment of keyword, sequence and classification search strategies for establishing biopharmaceutical drug-centric patent landscapes. The search results of both crude and sophisticated keyword search strategies, as well as of a sequence search strategy, were compared in terms of the key information retrieval quality indicators; the recall and the precision. Through analyses of the relevant retrieved documents, a quality assessment of keyword choice is provided, as well as determining focused IPC and Derwent Manual classification codes and terminology from original patent and Derwent documentation abstract titles. All of which can be used for setting up more efficient search strategies and facilitated document categorization.