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The impact of prescription drug monitoring programs on functional health

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  • Cotet-Grecu, Anca M.
  • Zanzalari, Danielle

Abstract

In the United States, policy responses to the opioid epidemic shifted opioid prescribing patterns. Such changes may have far-reaching implications beyond opioid misuse, raising concerns of impaired access to effective pain management. Unlike previous studies that focus on opioid prescribing and overdoses, this paper uses a broad measure of quality-of-life to capture both the intended effects of PDMPs on individuals who abuse or misuse opioids and incidental effects on legitimate users affected by changes in their pain management regimen. We find that failure to account for the staggered adoption of must-access PDMPs underestimates the benefits of this policy. After accounting for differential trends by age group and the staggered adoption of PDMPs, we find suggestive evidence of improvements in functioning. These gains are larger among demographic categories known to have higher rates of prescription drug (Rx) prescribing: older individuals, and individuals without a college degree—and not among groups with higher rates of non-medical prescription drug use.

Suggested Citation

  • Cotet-Grecu, Anca M. & Zanzalari, Danielle, 2026. "The impact of prescription drug monitoring programs on functional health," Economics & Human Biology, Elsevier, vol. 60(C).
    • Handle: RePEc:eee:ehbiol:v:60:y:2026:i:c:s1570677x25001030
    DOI: 10.1016/j.ehb.2025.101570
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    References listed on IDEAS

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    1. Kaestner, Robert & Ziedan, Engy, 2023. "Effects of prescription opioids on employment, earnings, marriage, disability and mortality: Evidence from state opioid control policies," Labour Economics, Elsevier, vol. 82(C).
    2. Crossley, Thomas F. & Kennedy, Steven, 2002. "The reliability of self-assessed health status," Journal of Health Economics, Elsevier, vol. 21(4), pages 643-658, July.
    3. Aliprantis, Dionissi & Fee, Kyle & Schweitzer, Mark E., 2023. "Opioids and the labor market," Labour Economics, Elsevier, vol. 85(C).
    4. Sacks, Daniel W. & Hollingsworth, Alex & Nguyen, Thuy & Simon, Kosali, 2021. "Can policy affect initiation of addictive substance use? Evidence from opioid prescribing," Journal of Health Economics, Elsevier, vol. 76(C).
    5. Sant’Anna, Pedro H.C. & Zhao, Jun, 2020. "Doubly robust difference-in-differences estimators," Journal of Econometrics, Elsevier, vol. 219(1), pages 101-122.
    6. Dhaval Dave & Bilge Erten & David Hummel & Pinar Keskin & Shuo Zhang, 2025. "Fighting abuse with prescription tracking: mandatory drug monitoring and intimate partner violence," Journal of Population Economics, Springer;European Society for Population Economics, vol. 38(3), pages 1-27, September.
    7. Simone Balestra & Helge Liebert & Nicole Maestas & Tisamarie B. Sherry, 2021. "Behavioral Responses to Supply-Side Drug Policy During the Opioid Epidemic," NBER Working Papers 29596, National Bureau of Economic Research, Inc.
    8. Dhaval Dave & Monica Deza & Brady Horn, 2021. "Prescription drug monitoring programs, opioid abuse, and crime," Southern Economic Journal, John Wiley & Sons, vol. 87(3), pages 808-848, January.
    9. Thomas C. Buchmueller & Colleen Carey, 2018. "The Effect of Prescription Drug Monitoring Programs on Opioid Utilization in Medicare," American Economic Journal: Economic Policy, American Economic Association, vol. 10(1), pages 77-112, February.
    10. Shishir Shakya & Jane E. Ruseski, 2023. "The effect of Prescription Drug Monitoring Programs on county‐level opioid prescribing practices and spillovers," Contemporary Economic Policy, Western Economic Association International, vol. 41(3), pages 435-454, July.
    11. Anca M. Grecu & Dhaval M. Dave & Henry Saffer, 2019. "Mandatory Access Prescription Drug Monitoring Programs and Prescription Drug Abuse," Journal of Policy Analysis and Management, John Wiley & Sons, Ltd., vol. 38(1), pages 181-209, January.
    12. Callaway, Brantly & Sant’Anna, Pedro H.C., 2021. "Difference-in-Differences with multiple time periods," Journal of Econometrics, Elsevier, vol. 225(2), pages 200-230.
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    JEL classification:

    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • K0 - Law and Economics - - General

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