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Association between iron deficiency and low-level lead poisoning in an urban primary care clinic

Author

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  • Wright, R.O.
  • Shannon, M.W.
  • Wright, R.J.
  • Hu, H.

Abstract

Objectives. The purpose of this study was to examine the association between iron deficiency and low-level lead poisoning. Methods. Data were collected in an urban primary care clinic from 3650 children aged 9 to 48 months. Iron deficiency was defined as a red cell mean corpuscular volume (MCV) of less than 70 fL and a red cell distribution width (RDW) of more than 14.5 in children younger than 2 years, and an MCV of less than 73 fL and RDW of more than 14.5 in those 2 years or older. Results. After adjustment for age, hemoglobin concentration, and insurance status, the odds ratios for iron deficiency predicting blood lead levels greater than or equal to 5 μg/dL and greater than or equal to 10 μg/dL were 1.63 (95% confidence interval [CI] = 1.29, 2.04) and 1.44 (95% CI = 1.004, 2.05). Conclusions. Iron deficiency is significantly associated with low-level lead poisoning in children aged 9 to 48 months.

Suggested Citation

  • Wright, R.O. & Shannon, M.W. & Wright, R.J. & Hu, H., 1999. "Association between iron deficiency and low-level lead poisoning in an urban primary care clinic," American Journal of Public Health, American Public Health Association, vol. 89(7), pages 1049-1053.
    • Handle: RePEc:aph:ajpbhl:1999:89:7:1049-1053_6
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    Cited by:

    1. Marsela Tanaka & Konstantinos Petsios & Stavroula K. Dikalioti & Stavroula Poulopoulou & Vassiliki Matziou & Stamatios Theocharis & Ioanna D. Pavlopoulou, 2018. "Lead Exposure and Associated Risk Factors among New Migrant Children Arriving in Greece," IJERPH, MDPI, vol. 15(6), pages 1-10, May.
    2. Chien-Juan Chen & Ting-Yi Lin & Chao-Ling Wang & Chi-Kung Ho & Hung-Yi Chuang & Hsin-Su Yu, 2019. "Interactive Effects between Chronic Lead Exposure and the Homeostatic Iron Regulator Transport HFE Polymorphism on the Human Red Blood Cell Mean Corpuscular Volume (MCV)," IJERPH, MDPI, vol. 16(3), pages 1-9, January.

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