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Clinical uncertainties, health service challenges, and ethical complexities of hiv 'test-and-treat': A systematic review

Author

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  • Kulkarni, S.P.
  • Shah, K.R.
  • Sarma, K.V.
  • Mahajan, A.P.

Abstract

Despite the HIV 'test-andtreat' strategy's promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, andethical complexities that may affect the test-and-treat strategy's success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation.

Suggested Citation

  • Kulkarni, S.P. & Shah, K.R. & Sarma, K.V. & Mahajan, A.P., 2013. "Clinical uncertainties, health service challenges, and ethical complexities of hiv 'test-and-treat': A systematic review," American Journal of Public Health, American Public Health Association, vol. 103(6), pages 14-23.
  • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2013.301273_4
    DOI: 10.2105/AJPH.2013.301273
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    Cited by:

    1. Watt, Melissa H. & Knettel, Brandon A. & Knippler, Elizabeth T. & Kisigo, Godfrey & Ngocho, James S. & Renju, Jenny & Rogathi, Jane & Sao, Saumya S. & Minja, Linda & Osaki, Haika & Mwamba, Rimel N. & , 2020. "The development of Maisha, a video-assisted counseling intervention to address HIV stigma at entry into antenatal care in Tanzania," Evaluation and Program Planning, Elsevier, vol. 83(C).

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