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Disparities in infant mortality: What's genetics got to do with it?

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  • David, R.
  • Collins Jr., J.

Abstract

Since 1950, dramatic advances in human genetics have occurred, racial disparities in infant mortality have widened, and the United States' international ranking in infant mortality has deteriorated. The quest for a "preterm birth gene" to explain racial differences is now under way. Scores of papers linking polymorphisms to preterm birth have appeared in the past few years. Is this strategy likely to reduce racial disparities? We reviewed broad epidemiological patterns that call this approach into question. Overall patterns of racial disparities in mortality and secular changes in rates of prematurity as well as birthweight patterns in infants of African immigrant populations contradict the genetic theory of race and point toward social mechanisms. We postulate that a causal link to class disparities in health exists.

Suggested Citation

  • David, R. & Collins Jr., J., 2007. "Disparities in infant mortality: What's genetics got to do with it?," American Journal of Public Health, American Public Health Association, vol. 97(7), pages 1191-1197.
  • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2005.068387_0
    DOI: 10.2105/AJPH.2005.068387
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    Cited by:

    1. Benjamin Sosnaud, 2022. "Reconceptualizing Measures of Black–White Disparity in Infant Mortality in U.S. Counties," Population Research and Policy Review, Springer;Southern Demographic Association (SDA), vol. 41(4), pages 1779-1808, August.
    2. Rosenthal, Lisa & Lobel, Marci, 2011. "Explaining racial disparities in adverse birth outcomes: Unique sources of stress for Black American women," Social Science & Medicine, Elsevier, vol. 72(6), pages 977-983, March.

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