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Minimally Important Differences Do Not Identify Responders to Treatment

Author

Listed:
  • Ron D Hays

    (UCLA Division of General Internal Medicine & Health Services Research, USA)

  • John D Peipert

    (Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, USA)

Abstract

The minimally important difference (MID) is “the average change in the domain of interest on the target measure among the subgroup of people deemed to change a minimal (but important) amount according to an ‘anchor’†[1]. The MID is used to determine if statistically significant group change is also large enough to be clinically meaningful. It is an additional consideration when interpreting group differences because very trivial differences can be statistically significant when the sample size is large.

Suggested Citation

  • Ron D Hays & John D Peipert, 2018. "Minimally Important Differences Do Not Identify Responders to Treatment," JOJ Sciences, Juniper Publishers Inc., vol. 1(1), pages 4-5, April.
    • Handle: RePEc:adp:oajojs:v:1:y:2018:i:1:p:4-5
    DOI: 10.19080/JOJS.2018.01.555552
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    Cited by:

    1. Ron D. Hays & Karen L. Spritzer & Steven P. Reise, 2021. "Using Item Response Theory to Identify Responders to Treatment: Examples with the Patient-Reported Outcomes Measurement Information System (PROMIS®) Physical Function Scale and Emotional Distress Comp," Psychometrika, Springer;The Psychometric Society, vol. 86(3), pages 781-792, September.

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