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A Rare Case of Thyrotoxic Periodic Paralysis Caused by TSH-Secreting Pituitary Adenoma: Case Report and Review of the Literature

Author

Listed:
  • Monami Koga
  • Takashi Fukuda
  • Kunitaka Murase
  • Ryoko Motonaga
  • Makito Tanabe
  • Toshihiko Yanase
  • Takashi Nomiyama

    (Department of Endocrinology and Diabetes Mellitus, Fukuoka University, Japan)

  • Toshirou Katsuta
  • Tooru Inoue

    (Department of Neurosurgery, Fukuoka University, Japan)

  • Hiroyuki Hayashi
  • Kazuki Nabeshima

    (Department of Pathology, Fukuoka University, Japan)

Abstract

A 28-year-old man manifested thyrotoxicosis and periodic quadriplegia with hypokalemia. Further examination showed that he had inappropriate TSH secretion and a pituitary tumor. He was suspected as having thyrotoxic periodic paralysis (TPP) due to TSH-secreting pituitary adenoma. Therefore, transsphenoidal surgery was performed. The adenoma only stained positive for TSH. TPP is mostly associated with Basedow’s disease. Our case is rare and the 6th reported TPP case caused by TSH-secreting pituitary adenoma. Our results suggest that TPP is not caused by an autoimmune mechanism, but thyroid hormones instead. We review five other rare cases of TPP caused by TSHsecreting pituitary adenoma.

Suggested Citation

  • Monami Koga & Takashi Fukuda & Kunitaka Murase & Ryoko Motonaga & Makito Tanabe & Toshihiko Yanase & Takashi Nomiyama & Toshirou Katsuta & Tooru Inoue & Hiroyuki Hayashi & Kazuki Nabeshima, 2017. "A Rare Case of Thyrotoxic Periodic Paralysis Caused by TSH-Secreting Pituitary Adenoma: Case Report and Review of the Literature," Journal of Endocrinology and Thyroid Research, Juniper Publishers Inc., vol. 1(1), pages 1-5, February.
    • Handle: RePEc:adp:oajetr:v:1:y:2017:i:1:p:1-5
    DOI: 10.19080/JETR.2017.01.555551
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    Keywords

    Journal of Endocrinology; Endocrinology Research ; Thyroid Research ; Endocrinology and Thyroid Research; juniper publishers :endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; juniper publishers journals;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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