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Early P1NP Suppression during Treatment of Low Bone Mass Postmenopausal Women with Risedronate 150 mg once-a Month

Author

Listed:
  • Gregorio S Riera-Espinoza
  • Yamila Cordero
  • Sandra Mendoza
  • Yuneci González

    (Unidad Metabólica, Centro Policlínico Valencia, South America)

  • Jenny Ramos
  • Jenny C Bello

    (Centro de Atención en Menopausia, CEAM, South America)

Abstract

The objective of this trial is to evaluate early response of rise dronate 150 mg once-a-month on N-terminal propeptide of procollagen type I (P1NP), a highly specific marker of bone formation in postmenopausal women with low bone mass (T-score below -1.5). Methods. P1NP and serum Beta-Cross Laps (CTx) were evaluated in 80 postmenopausal Venezuelan women with low bone mass (T-score below -1.5) either at lumbar spine or femoral neck (Lunar Prodigy VC 1.5%). All patients received rise dronate 150 mg/month and calcium citrate 1500 mg (315mg Calcium ion) plus Vitamin D 200 units/day. P1NP and CTx were measured on fully automated cobas e411 (Electro-chemiluminescence immunoassay analyzer).

Suggested Citation

  • Gregorio S Riera-Espinoza & Yamila Cordero & Sandra Mendoza & Yuneci González & Jenny Ramos & Jenny C Bello, 2017. "Early P1NP Suppression during Treatment of Low Bone Mass Postmenopausal Women with Risedronate 150 mg once-a Month," Orthopedics and Rheumatology Open Access Journals, Juniper Publishers Inc., vol. 8(2), pages 22-26, August.
    • Handle: RePEc:adp:joroaj:v:8:y:2017:i:2:p:22-26
    DOI: 10.19080/OROAJ.2017.08.555732
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