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Proposed Criteria for Early Detection of Leprotic Arthropathy

Author

Listed:
  • Mohamad I Hanafy
  • Hesham Hamoud
  • Abdulaziz A Mustafa

    (Department of Rheumatology, Al-Azhar University, Egypt)

  • Gamal A elkheshen

    (Department of Rheumatology Clinical Pathology, Al-Azhar University, Egypt)

Abstract

Leprosy is a chronic mycobacterial disease infectious in some cases primarily affecting the peripheral nervous system and secondarily involving skin specially the melanocyte and certain other tissues [1]. During the past decade, serological tests for detection of anti-mycobacterium leprae antibodies have been developed, among them, the enzyme-linked immunosorbent assay (ELIZA) using the purified phenolic glycolipid-I (PGL-I) from the cell wall as a mycobacterium leprae specific antigen has proved to be potentially useful for the serological study of leprosy patients, household contacts and normal individuals due to its simplicity, sensitivity as well as its capability of handling large numbers of sera simultaneously [2].

Suggested Citation

  • Mohamad I Hanafy & Hesham Hamoud & Abdulaziz A Mustafa & Gamal A elkheshen, 2017. "Proposed Criteria for Early Detection of Leprotic Arthropathy," Orthopedics and Rheumatology Open Access Journals, Juniper Publishers Inc., vol. 7(1), pages 21-28, May.
    • Handle: RePEc:adp:joroaj:v:7:y:2017:i:1:p:21-28
    DOI: 10.19080/OROAJ.2017.07.555706
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