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A Comparative Study on the Effects of Methylprednisolone Concentration on Human Chondrocyte Cell Metabolism in vitro

Author

Listed:
  • George Jacob
  • Shetty V

    (Department of Orthopedics Justice KS Hegde Medical Academy, Nitte University Deralakatte, India)

  • Shetty SM
  • Varughese J

    (Department of Orthopedics VPS Lakeshore Hospital, India)

  • Singh. RP
  • Malgatti SS
  • Kadage V

    (Regenerative medical services Pvt Ltd, 22, Shah industrial Estate, India)

Abstract

Osteoarthritis of the knee has been the most common form of arthritis encountered by clinicians today. Conservative modalities such as non steroidal anti inflammatory medications and intra articular corticosteroid have been employed to ameliorate the symptoms and delay total knee arthroplasty. In the past Corticosteroids have had an important role to play for decades in effective, economic and symptomatic relief in arthritis, but it may mask its true impact on the joint. The purpose of this study is to identify the effects of the concentration of methyl prednisolone on chondrocyte cell count, viability and CD44+ expression.

Suggested Citation

  • George Jacob & Shetty V & Shetty SM & Varughese J & Singh. RP & Malgatti SS & Kadage V, 2017. "A Comparative Study on the Effects of Methylprednisolone Concentration on Human Chondrocyte Cell Metabolism in vitro," Orthopedics and Rheumatology Open Access Journals, Juniper Publishers Inc., vol. 5(1), pages 42-45, March.
    • Handle: RePEc:adp:joroaj:v:5:y:2017:i:1:p:42-45
    DOI: 10.19080/OROAJ.2017.05.555660
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